Journal ArticleDOI
Asthma and serum levels of IgE ( Letter )
Tae. Platts-Mills,Sm. Pollart,Da. Mrazek,Klinnert,Giovanni Rolla,C. Bucca,Benjamin Burrows,Fd. Martinez,Marilyn Halonen,Barbee,Ra,Mg. Cline +11 more
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This article is published in The New England Journal of Medicine.The article was published on 1989-06-22. It has received 5 citations till now. The article focuses on the topics: Immunoglobulin E & Asthma.read more
Citations
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Journal ArticleDOI
Total serum IgE is associated with asthma independently of specific IgE levels. The Spanish Group of the European Study of Asthma
TL;DR: Findings reinforce previous evidence that asthma is associated with increased levels of total IgE, even in subjects negative for specific IgE to common aeroallergens, as well as individuals with current wheezing and bronchial responsiveness without attacks of asthma.
Journal ArticleDOI
Total serum IgE in trimellitic anhydride-induced asthma.
TL;DR: Although mean total IgE levels are significantly different between TMA-exposed workers with or without occupational asthma, the significant amount of overlap and poor sensitivity of the test preclude the use of this assay in the individual evaluation of these workers.
Journal ArticleDOI
Perioperative levels of total IgE correlate with outcomes of prolonged mechanical ventilation after cardiopulmonary bypass in pediatric patients.
TL;DR: A high preoperative tIgE level predisposes patients to an aggravated Th2 shift after protamine administration during CPB in association with increased risk of prolonged mechanical ventilation and medical intervention.
References
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Journal ArticleDOI
Association of asthma with serum IgE levels and skin-test reactivity to allergens.
TL;DR: It is concluded that asthma is almost always associated with some type of IgE-related reaction and therefore has an allergic basis, although not all the allergic stimuli that cause asthma appear to have been included in the battery of common aeroallergens the authors used to assess atopic status.
Journal ArticleDOI
IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2
J Pène,Françoise Rousset,Francine Brière,I Chrétien,J Y Bonnefoy,Hergen Spits,Takashi Yokota,Naoko Arai,Ken-ichi Arai,Jacques Banchereau +9 more
TL;DR: The IL-4-induced IgE production by B cells required T cells and monocytes but was specifically inhibited by an anti-IL-4 antiserum indicating that, although IL- 4 acts indirectly, it is responsible for the induction of IgE synthesis.
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The Course and Prognosis of Different Forms of Chronic Airways Obstruction in a Sample from the General Population
TL;DR: Examination of the course and prognosis in subjects selected from the general population who had chronic airflow obstruction at the time of their enrollment in a longitudinal epidemiologic study found better control of the progression of asthmatic bronchitis with therapy may explain its more favorable prognosis.
Journal Article
Morphological studies of bronchial mucosal biopsies from asthmatics before and after ten years of treatment with inhaled steroids
TL;DR: Biopsies from six patients with severe bronchial asthma were studied before and after ten years of daily treatment with inhaled steroids, finding the number of inflammatory cells was significantly reduced compared to that before treatment and was not different from the control biopsies.
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Epidemiology of acute asthma: IgE antibodies to common inhalant allergens as a risk factor for emergency room visits
TL;DR: It is established that, with acute attacks of asthma as a marker for adult asthma, the presence of serum IgE Abs to common inhalant allergens is a major risk factor.