Journal ArticleDOI
Basic character of rare earth metal alkoxides. Utilization in catalytic C-C bond-forming reactions and catalytic asymmetric nitroaldol reactions
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In this article, the authors reported several carbon-carbon bond-forming reactions catalyzed by rare earth metal alkoxides and their application to a catalytic asymmetric nitroaldol reaction.Abstract:
In a recent paper, the authors reported that Zr(O-t-Bu){sub 4} was an efficient and convenient basic reagent in organic synthesis. However, all reactions examined were performed with stoichiometric quantities of the reagent. The authors envisioned that rare earth metal alkoxides would be stronger bases than group 4 metal alkoxides due to the lower ionization potential (ca. 5.4-6.4 eV) and the lower electronegativity (1.1-1.3) of rare earth elements; thus, the catalytic use of rare earth metal alkoxides in organic synthesis was expected. Although a variety of rare earth metal alkoxides have been prepared for the last three decades, to the authors knowledge, there have been few reports concerning the basicity of rare earth metal alkoxides. Herein, the authors report several carbon-carbon bond-forming reactions catalyzed by rare earth metal alkoxides and their application to a catalytic asymmetric nitroaldol reaction.read more
Citations
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Quantum Chemical Studies of Mechanisms and Stereoselectivities of Organocatalytic Reactions
TL;DR: In this paper, the specific modes of action of new organic catalysts were investigated and the results showed that density functio-functio (DFF) is the most common mode of action for these new catalysts.
Journal ArticleDOI
Ein praktikabler und robuster zwitterionischer kooperativer Lewis‐Säure‐/Acetat‐/Benzimidazolium‐Katalysator für direkte 1,4‐Additionen
TL;DR: In this paper , a polyfunktionelle katalytischen analyzer is vorgestellt, der eine außergewöhnliche Effizienz bei direkten 1,4-additionen ermöglicht.
Book ChapterDOI
Recent Advances in Rare Earth Metal Asymmetric Catalysis Toward Practical Synthesis of Therapeutics
TL;DR: In this article, two case studies regarding the development of rare earth metal-based asymmetric catalysts are summarized, with particular focus on the process of refining catalysts amenable to industrial applications.
Journal ArticleDOI
Enantioselective Henry Reaction Catalysed by Chiral-copper(II) Complexes: Chirality Effect Derived from Ligand Backbone and Side-chain
TL;DR: In this paper , two diastereopure camphor-derived iminomethylpyridine ligands were resolved and structurally characterised by single-crystal X-ray diffraction.
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