Biomechanics of abdominal aortic aneurysm in the presence of endoluminal thrombus: experimental characterisation and structural static computational analysis.
E. Di Martino,Sara Mantero,Fabio Inzoli,Germano Melissano,D. Astore,Roberto Chiesa,Roberto Fumero +6 more
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TLDR
Well organised thrombus reduces the effect of the pressure load on the aneurysmal aortic wall and the numerical analyses show the mechanical behaviour of AAA as a function of lumen eccentricity and biomechanical parameters.About:
This article is published in European Journal of Vascular and Endovascular Surgery.The article was published on 1998-04-01 and is currently open access. It has received 204 citations till now. The article focuses on the topics: Thrombus & Abdominal aortic aneurysm.read more
Citations
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Prediction of rupture risk in abdominal aortic aneurysm during observation: Wall stress versus diameter
TL;DR: For AAAs under observation, peak AAA wall stress seems superior to diameter in differentiating patients who will experience catastrophic outcome, and with proportional hazards analysis, peak wall stress and gender were the only significant independent predictors of rupture.
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In vivo analysis of mechanical wall stress and abdominal aortic aneurysm rupture risk.
Mark F. Fillinger,Madhavan L. Raghavan,Steven P. Marra,Jack L. Cronenwett,Francis E. Kennedy +4 more
TL;DR: Calculation of wall stress with computer modeling of three-dimensional AAA geometry appears to assess rupture risk more accurately than AAA diameter or other previously proposed clinical indices.
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Biomechanics of abdominal aortic aneurysm
TL;DR: The history and state-of-the-art of this field is reviewed--including investigations into the biomechanical behavior of AAA tissues, modeling AAA wall stress and factors which influence it, and the potential clinical utility of these estimates in predicting AAA rupture.
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Wall stress distribution on three-dimensionally reconstructed models of human abdominal aortic aneurysm.
Madhavan L. Raghavan,David A. Vorp,Michael P. Federle,Michel S. Makaroun,Marshall W. Webster +4 more
TL;DR: A methodology to noninvasively estimate the in vivo wall stress distribution for actual AAAs on a patient-to-patient basis is developed and may allow for the evaluation of an individual AAA's rupture risk on a more biophysically sound basis than the widely used 5-cm AAA diameter criterion.
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Fluid–structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysm
TL;DR: The complex mechanical interaction between blood flow and wall dynamics in a three dimensional custom model of a patient AAA was studied by means of computational coupled fluid-structure interaction analysis, providing a quantitative local evaluation of the stresses due to local structural and fluid dynamic conditions.
References
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Multicenter prospective study of nonruptured abdominal aortic aneurysm. Part II. Variables predicting morbidity and mortality
TL;DR: The patient population and operative management of 666 patients who had surgery for nonruptured abdominal aortic aneurysms and the variables that are associated with each complication are described by chi-square and logistic regression analysis.
Journal Article
Actuarial analysis of variables associated with rupture of small abdominal aortic aneurysms
Jack L. Cronenwett,T. F. Murphy,Gerald B. Zelenock,Walter M. Whitehouse,Lindenauer Sm,Linda M. Graham,L. E. Quint,Terry M. Silver,James C. Stanley +8 more
TL;DR: Diastolic blood pressure, initial aneurysm anteroposterior diameter, and degree of obstructive pulmonary disease were independently predictive of rupture, and actuarial rupture rates were predicted for patients with selected values of these three covariates.
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The composition and mechanical properties of abdominal aortic aneurysms
Chang M. He,Margot R. Roach +1 more
TL;DR: Both the composition and mechanical properties of abdominal aortic aneurysms are different from those of nonaneurysmal aortas, and the aneurYSms were stiffer and the volume fractions of collagen and ground substance were increased, whereas the volume fraction of elastin and muscle were decreased in aneuryms.
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Failure properties of passive human aortic tissue. II—Biaxial tension tests
Dinesh Mohan,John W. Melvin +1 more
TL;DR: Ultimate stress and extension ratio values have been calculated for specimens tested in the longitudinal and transverse directions of the aorta for descending mid-thoracic aortas.
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Pathogenesis of abdominal aortic aneurysm.
TL;DR: The pathogenesis of abdominal aortic aneurysm is a key event that shifts the load produced by blood pressure on to collagen, and further dilatation and rupture of the aorta depend on the physical properties of the collagen present.