Journal ArticleDOI
Carbon-13 Magnetic Resonance Studies of Azoles. Tautomerism, Shift Reagent Effects, and Solvent Effects
TLDR
The effects of substitution, lanthanide-shift reagents, solvent changes, and tautomerism were investigated in this article, where it was concluded that chemical shifts are of limited value to ascertain the positions of tautomers.Abstract:
The effects of substitution, lanthanide-shift reagents, solvent changes, and tautomerism were investigated on
the ^(13)C chemical shifts of pyrrole, pyrazole, imidazole, s- and v-triazole, and tetrazole. It was concluded that
^(13)C chemical shifts are of limited value to ascertain the positions of tautomeric equilibrium for rapidly interconverting azole tautomers.read more
Citations
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Journal ArticleDOI
Tautomeric equilibria in relation to pi-electron delocalization.
Book ChapterDOI
The Tautomerism of Heterocycles: Five-membered Rings with Two or More Heteroatoms
Journal ArticleDOI
N‐polyazolylmethanes. 1. Synthesis and nmr study of N,N′‐diazolylmethanes
Sebastian Juliá,Pilar Sala,José Del Mazo,Manuel Sancho,Carmen Ochoa,José Elguero,Jean-Pierre Fayet,M. C. Vertut +7 more
TL;DR: In this paper, the relative amounts of isomeric mixtures obtained with asymmetric azoles or with equimolar mixtures of azoles are compared with literature results on monoalkylation of azole.
Book ChapterDOI
Recent Advances in Tetrazole Chemistry
TL;DR: In this paper, the development of tetrazole chemistry from 1965 to 1975 is discussed, including the applications of modern physical techniques to tetrazoles derivatives and studies of pharmacologically active tetrazolines, particularly replacement of the carboxylic acid group in known active molecules by its analog.