Journal ArticleDOI
Chiral separation of monoterpenes using mixtures of sulfated β-cyclodextrins and α-cyclodextrin as chiral additives in the reversed-polarity capillary electrophoresis mode
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TLDR
In this article, the use of mixtures of sulfated β-cyclodextrins and native α-cyclodesxtrin as chiral additives in capillary electrophoresis was evaluated for the chiral resolution of neutral, cyclic and bicyclic monoterpenes, including α-pinene, β-pinenes, camphene and limonene.About:
This article is published in Journal of Chromatography A.The article was published on 1997-01-24. It has received 59 citations till now. The article focuses on the topics: Chiral resolution & Enantiomer.read more
Citations
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Journal ArticleDOI
Enantioselective determination by capillary electrophoresis with cyclodextrins as chiral selectors.
TL;DR: This review surveys the separation of enantiomers by capillary electrophoresis using cyclodextrins as chiral selector and selected applications to real samples such as pharmaceutical formulations, biological and medical samples are discussed.
Journal ArticleDOI
Enantioseparations in capillary electromigration techniques: recent developments and future trends
TL;DR: This review summarizes the current status of enantioseparations using capillary electromigration techniques and gives the authors insights on the selected fundamental aspects and future trends in this field.
Journal ArticleDOI
Chiral separation principles in capillary electrophoresis
Gerald Gübitz,Martin G. Schmid +1 more
TL;DR: Capillary electrophoretic techniques for the separation of enantiomers are reviewed in this paper, where a comprehensive collection of applications to drugs and other compounds of interest is given in tables.
Journal ArticleDOI
Separation selectivity in chiral capillary electrophoresis with charged selectors
TL;DR: In this article, a review summarizes the separation selectivity in chiral capillary electrophoresis with charged selectors, i.e., the absolute and the relative mobility difference between the enantiomers, the ratio of apparent mobilities and ratio of effective mobilities as well as the intrinsic selectivity, are compared.
Journal ArticleDOI
Controlling enantioselectivity in chiral capillary electrophoresis with inclusion–complexation
TL;DR: The review presents a list of the latest separation of enantiomers by CE where inclusion-complexation plays a key role in the stereoselective separation mechanism.
References
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Journal ArticleDOI
Theoretical aspects of chiral separation in capillary electrophoresis: I. Initial evaluation of a model
TL;DR: In this article, a simple model for the separation of pairs of enantiomeric molecules in capillary electrophoresis is presented, which shows that the degree of separation depends on the concentration of chiral selector, and that there is an optimum concentration.
Journal ArticleDOI
Optical resolution of drugs by capillary electrophoretic techniques
Hiroyuki Nishi,Shigeru Terabe +1 more
TL;DR: In this article, a review of the optical resolution of drugs by capillary electrophoretic (CE) techniques is presented, which is mainly achieved through the modification of the separation solution with chiral additives such as cyclodextrins or proteins.
Journal ArticleDOI
Chiral resolution of cationic drugs of forensic interest by capillary electrophoresis with mixtures of neutral and anionic cyclodextrins.
Ira S. Lurie,Robert F. X. Klein,Terry A. Dal Cason,Michael J. LeBelle,Rudolf. Brenneisen,Robert Weinberger +5 more
TL;DR: The use of mixtures of the neutral and the anionic CD (beta-CD sulfobutyl ether IV) was found suitable for the analysis of illicit amphetamine, methamphetamine, methcathinone, and propoxyphene.
Journal ArticleDOI
Chiral separation by cyclodextrin-modified micellar electrokinetic chromatography
TL;DR: Chiral separation by micellar electrokinetic chromatography (MEKC), which permits the separation of uncharged or electrically neutral compounds by the electrophoretic technique, was achieved through the addition of cyclodextrins (CDs) to sodium dodecyl sulphate (SDS) micelle solution.
Journal ArticleDOI
Application of Sulfated Cyclodextrins to Chiral Separations by Capillary Zone Electrophoresis
Apryll M. Stalcup,Kyung H. Gahm +1 more
TL;DR: Mixtures of randomly substituted sulfated cyclodextrins were successfully used as chiral additives for the enantioseparation of 56 compounds of pharmaceutical interest, including anesthetics, antiarrhythmics, antidepressants, anticonvulsants, antihistamines, antihypertensives, antimalarials, relaxants, and bronchodilators.
Related Papers (5)
Theoretical aspects of chiral separation in capillary electrophoresis: I. Initial evaluation of a model
Application of Sulfated Cyclodextrins to Chiral Separations by Capillary Zone Electrophoresis
Apryll M. Stalcup,Kyung H. Gahm +1 more