Journal ArticleDOI
Circulatory effects of interruption and stimulation of cardiac vagal afferents.
B. ÖBerg,Saxon William White +1 more
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The influence of the rhythmic activity in cardiac vagal afferents on the circulation was analyzed in chloralose-anesthetized cats by observing the cardiovascular responses to sudden interruption of this activity and to afferent stimulation of the cardiac nerves.Abstract:
The influence of the rhythmic activity in cardiac vagal afferents on the circulation was analyzed in chloralose-anesthetized cats by observing the cardiovascular responses to sudden interruption of this activity and to afferent stimulation of the cardiac nerves. The evoked responses were compared with those produced by “unloading” and stimulation of arterial baroreceptors. — Elimination of the impulse traffic in vagal afferents produced a blood pressure rise, a tachycardia and vasoconstrictions in skeletal muscle, intestine and kidney, indicating a tonic restraint of these afferents on the medullary vasomotor centre. The responses were generally moderate in the presence of normally functioning arterial baroreceptors but were pronounced after elimination of “buffering” influences from these receptors. — Comparisons of the inhibitory influences from vagal cardiac afferents and baroreceptor afferents, respectively, on the vasomotor centre indicated that the former were preferentially directed to neurons controlling the efferent discharge to the heart and the renal vessels. There was no evidence for a particularly strong engagement of the capacitance vessels in reflex patterns mediated through cardiac afferents. — Low frequency afferent stimulation of the cardiac nerves generally induced a profound brady-cardia, which was probably due to stimulation of fibres not normally tonically active.read more
Citations
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Vagal modulation of responses elicited by stimulation of the aortic depressor nerve in neurons of the rostral ventrolateral medulla oblongata in the rat.
TL;DR: It is proposed that inhibitory inteneurons that mediate late inhibition to rostral ventrolateral medulla oblongata neurons may lie within the caudal part of the nucleus of the solitary tract, implicated in long-term modulation of sympathetic outflows in response to changes in the activation of visceral receptors supplied by vagus afferents.
Journal ArticleDOI
Attenuation of cardiac sympathetic drive in experimental myocardial ischemia in dogs
TL;DR: The results of this study suggest that acute coronary occlusion produces a cardiocardiac depressor reflex with attenuation of sympathetic discharge to the heart, which gives way to the baroreceptor reflex when aortic pressure drops to critically low levels.
Journal ArticleDOI
Responses of renal hemodynamics and function to acute volume expansion in the conscious dog.
TL;DR: These data indicate that in the intact conscious dog -vagal afferent mechanisms play an important role in mediating the diuretic and natriuretic responses to acute volume expansion, whereas the changes in renal hemodynamics that occur with volume expansion appear independent of reflex pathways.
Journal ArticleDOI
Cardiac volume receptor reflex in borderline hypertensive rats.
Gerald F. DiBona,S Y Jones +1 more
TL;DR: With increased dietary NaCl intake (8% NaCl), borderline hypertensive rats (BHR) develop hypertension and exhibit an exaggerated natriuresis in response to intravenous isotonic saline volume expansion.
Research report Neurotransmission of the Bezold-Jarisch reflex in the nucleus tractus solitarii of sino-aortic deafferentated rats
TL;DR: In this article, the effect of kynurenic acid on the B-J reflex was investigated in sino-aortic deafferentated SAD and sham-operated SO unanesthetized rats.
References
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Journal Article
Comparative studies on the adrenergic neuro-hormonal control of resistance and capacitance blood vessels in the cat.
Journal ArticleDOI
Vagal Afferent Fibres
TL;DR: The cervical vagus consists of about 30 thousand fibres of which about 24 000 are sensory in function and about 3 thousand are myelinated and have been the centre of attraction in electrophysiological studies chiefly owing to the relative ease with which impulses can be recorded in them.
Journal ArticleDOI
A study of right and left atrial receptors.
TL;DR: It will be shown that all such receptors encountered so far arose in the right and left atria of the heart; these will be referred to as type B atrial receptors.
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