Clinical research in a nutshell: How to embark on research journey?

TLDR: This work aims to provide "critical points to take into account when developing a research from the idea to the final publication" and will guide those who need to delve deeper the clinical research panorama and write a clinical research paper.

Abstract: Background: Medical students, interns and residents at all levels needs a boost dose of simple plan and exemplified written format to participate in medical (clinical/toxicological) research. Aim: Herein, we aim to provide "critical points to take into account when developing a research from the idea to the final publication". This will guide those who need to delve deeper the clinical research panorama and write a clinical research paper. Methods: We have performed a review on available tools that provide information on how to conduct a research study and develop a manuscript intended for publication. In order to initiate any clinical research activity, an initial assessment of the current routine clinical practice is a pre-requisite to conceive and design the research. In "Introduction", a clinical researcher should inform the readers about the clinical implications of the study and should anticipate new practices. The author should also bring the statistical outputs in organized predefined titled tables, no matter how many initially; however, later may deduce to the minimum number of tables. Results: The researcher or investigator should provide anticipated results for the proposed protocol and detailed results for the manuscript. The initial results are the demographics and past medical/medication/ morbidities. Then should narrow down more specific to the main findings. Each results illustrated in tables should stands as the discussion area. Therefore, tables must follow an uphill fashion and upward direction to the final conclusions. Discussions: The tip of the iceberg is the main findings and