COVID-19 and the cardiovascular system-current knowledge and future perspectives
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TLDR
A mini review aims to provide an update on the current knowledge and perspectives on areas of future research on SARS-CoV-2, its causative viral agent, and emerging evidence on propensity of this virus to attack cardiovascular system.Abstract:
The current coronavirus disease 2019 (COVID-19) pandemic has had devastating impact on populations around the world. The high mortality rates in patients with COVID-19 has been attributed to the influence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), its causative viral agent, on several physiological systems in human body, including the respiratory, cardiovascular, and neurological systems. There is emerging evidence on propensity of this virus to attack cardiovascular system. However, various pathophysiological mechanisms by which SARS-CoV-2 interacts with cardiovascular system and leads to high morbidity and mortality, including cardiovascular complications, are poorly understood. This mini review aims to provide an update on the current knowledge and perspectives on areas of future research.read more
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References
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Journal ArticleDOI
Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19).
Tao Guo,Yongzhen Fan,Ming Chen,Xiaoyan Wu,Lin Zhang,Tao He,Hairong Wang,Jing Wan,Xinghuan Wang,Zhibing Lu +9 more
TL;DR: This case series study evaluates the association of underlying cardiovascular disease and myocardial injury on fatal outcomes in patients with coronavirus disease 2019 (COVID-19).
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Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19).
Valentina O. Puntmann,M. Ludovica Carerj,Imke Wieters,Masia Fahim,Christophe T. Arendt,Jedrzej Hoffmann,Anastasia Shchendrygina,Felicitas Escher,Mariuca Vasa-Nicotera,Andreas M. Zeiher,Maria J G T Vehreschild,Eike Nagel +11 more
TL;DR: Cardiac magnetic resonance imaging revealed cardiac involvement and ongoing myocardial inflammation in patients with recent coronavirus disease 2019, which was independent of preexisting conditions, severity and overall course of the acute illness, and the time from the original diagnosis.
Journal ArticleDOI
COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives.
TL;DR: The interaction between the viral spike protein and angiotensin-converting enzyme 2, which triggers entry of the virus into host cells, is likely to be involved in the cardiovascular manifestations of COVID-19.
Journal ArticleDOI
Recognizing COVID-19-related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management.
Bhurint Siripanthong,Saman Nazarian,Daniele Muser,Rajat Deo,Pasquale Santangeli,Mohammed Y Khanji,Mohammed Y Khanji,Leslie T. Cooper,C. Anwar A. Chahal,C. Anwar A. Chahal,C. Anwar A. Chahal +10 more
TL;DR: Clinicians should be vigilant to provide prompt monitoring and treatments of COVID-19 patients and an endomyocardial biopsy may help identify active cardiac infection through viral genome amplification and possibly refine the treatment risks of systemic immunosuppression.
Journal ArticleDOI
Out-of-Hospital Cardiac Arrest during the Covid-19 Outbreak in Italy.
Enrico Baldi,Giuseppe Maria Sechi,Claudio Mare,Fabrizio Canevari,Antonella Brancaglione,Roberto Primi,Catherine Klersy,Alessandra Palo,Enrico Contri,Vincenza Ronchi,Giorgio Beretta,Francesca Reali,Pierpaolo Parogni,Fabio Facchin,Davide Bua,Ugo Rizzi,Daniele Bussi,Simone Ruggeri,Luigi Oltrona Visconti,Simone Savastano +19 more
TL;DR: Out- of-Hospital Cardiac Arrest and Covid-19 From February 21 through April 1, 2019, a total of 229 cases of out-of-hospital cardiac arrest were reported in four provinces of Lombardy, Italy.
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