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Journal ArticleDOI

Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro

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TLDR
Considering its water-solubility and high inhibitory growth effect, crocin is the more promising saffron compound to be assayed as a cancer therapeutic agent.
About
This article is published in Cancer Letters.The article was published on 1996-02-27. It has received 381 citations till now. The article focuses on the topics: Safranal & Picrocrocin.

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Handbook of Herbs and Spices

K. V. Peter
TL;DR: Herbs, spices and their active components as natural antimicrobials in foods Effect of natural antioxidants in herbs and spices on shelf life of foods is studied.
Journal ArticleDOI

Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice

TL;DR: It is concluded that aqueous and ethanolic extracts of saffron stigma and petal have an antinociceptive effect, as well as acute and/or chronic anti-inflammatory activity.
Journal ArticleDOI

Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.).

TL;DR: A growing body of research has demonstrated that saffron extract itself and its main constituents, the carotenoids, possess chemopreventive properties against cancer.
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Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials

TL;DR: It is suggested that future research be warranted that will define the possible use of saffron as effective anticancer and chemopreventive agent in clinical trials.
Journal ArticleDOI

Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents

TL;DR: The DPPH radical scavenging activity of a natural product that possesses biological properties, an extract of Crocus sativus L. (saffron), grown in Crocos, Kozani (Greece), and some of its bioactive constituents (crocin, safranal) was studied.
References
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Animal Cell Culture

Book

Animal cell culture : a practical approach

TL;DR: The present work focuses on cell line preservation and characterization, and in situ hybridization Index, which describes the steps towards and away from serum-free, chemically defined media for mammalian cell culture.
Journal Article

Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay

TL;DR: It is shown that reduction of M TT to MTT-formazan by cells is dependent on the amount of MTT in the incubation medium and can be used to estimate cell numbers in a simple chemosensitivity assay the results of which agree well with a commonly used clonogenic assay.
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Dietary vitamin A and human lung cancer.

TL;DR: Five‐year follow-up results for 8,278 men who in mail surveys had reported their cigarette smoking and dietary habits showed an index for vitamin A intake to be negatively associated with lung cancer incidence at all levels of cigarette smoking.
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