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Crystal structure of (E)-2-((2-methoxy-3-pyridyl)methylene)-7-fluoro-3,4-dihydronaphthalen-1(2H)-one, C17H14FNO2

Zhang Xiao-Fan, +1 more
- 01 May 2021 - 
- Vol. 236, Iss: 3, pp 507-509
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This article is published in Zeitschrift Fur Kristallographie-new Crystal Structures.The article was published on 2021-05-01 and is currently open access. It has received 4 citations till now. The article focuses on the topics: Methylene & Crystal structure.

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Crystal structure of (3E,5E)-3,5-bis-4-methoxy-3-(trifluoromethyl)benzylidene)-1-methylpiperidin-4-one, C24H21F6NO3

TL;DR: In this article, a monoclinic P21/c (no. 14), a = 16.6493(9) Å, b = 15.3005(8)Å, c = 8.8554(5)À, β = 99.746(6)°, V = 2223.3(2)Á3, Z = 4, Rgt(F) = 0.0444, wRref(F2)= 0.1094, T = 100 K.
Journal ArticleDOI

Crystal structure of E-7-fluoro-2-(2-(trifluoromethyl)benzylidene)-3,4-dihydronaphthalen-1(2H)-one, C18H12F4O

TL;DR: In this article , the triclinic trichloric P1̄ (no. 2), a = 7.9400(8) and b = 8.1071(9) Å, c = 13.3238(15) and α = 89.394 (9 ) ° $89.394\left(9\right)^{\circ} $ , β = 76.343 ( 9 ) °$76.
References
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A short history of SHELX

TL;DR: This paper could serve as a general literature citation when one or more of the open-source SH ELX programs (and the Bruker AXS version SHELXTL) are employed in the course of a crystal-structure determination.
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Crystal structure refinement with SHELXL

TL;DR: New features added to the refinement program SHELXL since 2008 are described and explained.
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Role of Microglia in CNS Autoimmunity

TL;DR: The current knowledge regarding the highly diverse and complex function of microglia during CNS autoimmunity in either promoting tissue injury or tissue repair in MS is summarized.
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The role of microglial activation in disease progression.

TL;DR: Modulation of microglial activation for therapeutic purposes must consider suppressing deleterious effects of these cells, while simultaneously preserving their protective functions.
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Sesquiterpene dimer (DSF-52) from Artemisia argyi inhibits microglia-mediated neuroinflammation via suppression of NF-κB, JNK/p38 MAPKs and Jak2/Stat3 signaling pathways

TL;DR: The inhibitory ability of DSF-52 on microglia- mediated neuroinflammation may offer a novel neuroprotective modality and could be potentially useful in inflammation-mediated neurodegenerative diseases.