Journal ArticleDOI
Cyclization of squalene-2,3-oxide to lanosterol in a cell-free system from Phycomyces blakesleeanus
E.I. Mercer,M.W. Johnson +1 more
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TLDR
A cell-free enzyme preparation from Phycomyces blakesleeanus is described which catalysed the cyclization of the [ 14C]squalene-2,3-oxide to [14C]lanosterol.About:
This article is published in Phytochemistry.The article was published on 1969-12-01. It has received 18 citations till now. The article focuses on the topics: Phycomyces blakesleeanus & Lanosterol.read more
Citations
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Journal ArticleDOI
Sterols of the fungi: Distribution and biosynthesis
TL;DR: The composition and biosynthesis of ergosterol in these organisms and comparison to plant and animal sterol formation are made are made.
Journal ArticleDOI
The Biosynthesis of Ergosterol
TL;DR: The paper concentrates upon the post-squalene segment of the process as it occurs in fungi because the commercially important inhibitors of ergosterol biosynthesis are fungicides that block steps within that process.
Book ChapterDOI
The Biochemistry of Plant Sterols
TL;DR: The isolation and identification of a particular compound falls into the general realm of structural elucidation, which can become complicated, especially for an unusual sterol, however, for the common dominant structures, advances in chromatography and spectroscopy allow a simple procedure.
Book ChapterDOI
The Biosynthesis of Plant Sterols
TL;DR: The studies of phytosterol biosynthesis have been rewarded by the recognition of several intriguing mechanistic differences not only between animals and plants but also between particular classes of plants.
Journal ArticleDOI
Concerning the Role of Lanosterol and Cycloartenol in Steroid Biosynthesis
TL;DR: Observations made in vivo with an alga and with tissue cultures of an angiosperm indicate that lanosta-8,24-dien-3β-ol (lanosterol) and its 9,19-cyclo derivative (cycloartenol) are both acceptable precursors in the biosynthesis of the major sterols of photosynthetic organisms.
References
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Determination of serum proteins by means of the biuret reaction.
TL;DR: An investigation of the biochemical changes following experimental liver injury felt the need of a simple, rapid, and accurate method for determining the protein fractions in small amounts of serum and began with Kingsley’s biuret procedure.
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The biosynthesis of cholesterol from acetate-1-C14 by cellular fractions of rat liver.
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2,3-oxidosqualene, an intermediate in the biological synthesis of sterols from squalene.
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Enzymic conversion of squalene 2,3-oxide to lanosterol and cholesterol.
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La biosynthèse des stérols dans les tissus de tabac cultivés in vitro—II. : Particularités de la biosynthèse des phytostérols des tissus de tabac cultivés in vitro
TL;DR: It is suggested that cycloartenol may replace lanosterol as an intermediate in the biosynthesis of phytosterols in tobacco tissue cultures.