Journal ArticleDOI
Cycloadditions onto Methylene‐ and Alkylidenecyclopropane Derivatives
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TLDR
In this paper, all the reactions which involve the exocyclic double bond of alkylidenecyclopropanes in cycloaddition processes are dealt with.Abstract:
Alkylidenecyclopropanes are a peculiar class of olefinic compounds characterized by a high ring strain, but at the same time a sufficient stability to permit their use in organic synthesis. The strain associated with the structure of these compounds is in general responsible for the good reactivity of the carbon-carbon double bond, even in sterically encumbered substrates. The key role of these compounds in organic synthesis resides in the exclusive, and by far the most useful, possibility of the introduction of a cyclopropyl ring in a more complex molecule through reactions onto the exocyclic double bond. For this reason the investigations on the synthesis and reactivity of these compounds has exploded in the last decade. This article will deal with all the reactions which involve the exocyclic double bond of alkylidenecyclopropanes in cycloaddition processes. Albeit most of the reactions are true pericyclic cycloaddition processes, also those reactions which lead to cycles by stepwise processes will be reported with comments on the mechanism.read more
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Journal ArticleDOI
Cascade cyclization reactions of alkylidenecyclopropanes for the construction of polycyclic lactams and lactones by visible light photoredox catalysis
TL;DR: In this article, a visible light photocatalytic cascade cyclization reaction of alkylidenecyclopropanes for the rapid construction of seven and eight-membered ring-containing polycyclic lactams and lactones has been developed.
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Book ChapterDOI
Cycloadditions onto methylene- and alkylidenecyclopropane derivatives
TL;DR: In this paper, all the reactions which involve the exocyclic double bond of alkylidenecyclopropanes in cycloaddition processes are dealt with.
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