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Patent

Cytocompatible alginate gels

TLDR
In this article, a method of making cytocompatible alginate gels and their use in the treatment of cardiomyopathy was described, which relates to the present invention.
Abstract
The present invention relates to a method of making cytocompatible alginate gels and their use in the treatment of cardiomyopathy.

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Methods and compositions for treating tissue using silk proteins

TL;DR: In this paper, a self-reinforcing composite biomatrix, methods of manufacture and use, and Kits including delivery devices suitable for delivering the compositions are also disclosed, in some embodiments, the composition can include at least three components.
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Hydrogel bioscaffoldings and biomedical device coatings

TL;DR: In this article, the authors describe bioscaffoldings formed of hydrogels that are crosslinked in situ in an infarcted region of the heart (myocardium) by a Michael's addition reaction or by a disulfide bond formed by an oxidative process.
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Modified two-component gelation systems, methods of use and methods of manufacture

TL;DR: In this article, the authors describe a post-myocardial infarction (PMI) treatment using a mixture of functionalized polymer and growth factor in a dual-bore injection device.
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Methods of modifying myocardial infarction expansion

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Instrumentation and method for positioning and securing a graft

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References
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Journal ArticleDOI

Effect of pegylation on pharmaceuticals

TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
Journal ArticleDOI

Alginate as immobilization matrix for cells

TL;DR: This review evaluates the potential of entrapment of cells within spheres of Ca2+ alginate gels on the basis of the current knowledge of structural and functional relationships in alginATE gels.
Journal ArticleDOI

Protein release from alginate matrices.

TL;DR: By selection of the type of alginate and coating agent, the pore size, degradation rate, and ultimately release kinetics can be controlled.
Journal ArticleDOI

Bioengineered Cardiac Grafts A New Approach to Repair the Infarcted Myocardium

TL;DR: After implantation into the infarcted myocardium, the biografts stimulated intense neovascularization and attenuated LV dilatation and failure in experimental rats compared with controls, suggesting alginate scaffolds provide a conducive environment to facilitate the 3D culturing of cardiac cells.
Journal ArticleDOI

Production of Unilamellar Vesicles Using an Inverted Emulsion

TL;DR: In this article, a method for the controlled assembly of unilamellar vesicles consisting of bilayers assembled one leaflet at a time was investigated, using water-in-oil emulsions stabilized by the material for the assembly.