Journal ArticleDOI
Determination of tablet strength by the diametral compression test
John T. Fell,JM Newton +1 more
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TLDR
It has been shown that to obtain reproducible results for the strength of tablets prepared at a given compression force, the tablet must break in such a manner that the tensile stress is the major stress.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1970-05-01. It has received 1256 citations till now. The article focuses on the topics: Ultimate tensile strength & Compressive strength.read more
Citations
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Biomedical applications of collagen
TL;DR: In this paper, the authors reviewed biomedical applications of collagen including the collagen film, which was developed as a matrix system for evaluation of tissue calcification and for the embedding of a single cell suspension for tumorigenic study.
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Physical quality of pelleted animal feed 1. Criteria for pellet quality
M. Thomas,A.F.B. van der Poel +1 more
TL;DR: An overview is given on the binding mechanisms in pelleted animal feeds and it is concluded that binding in pellets most probably is due to solubilisation and subsequent crystallisation of feedstuff components e.g. starch, sugars, fats or ‘liquid necking.
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Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction.
TL;DR: It is proposed that the compactibility profile (tensile strength vs. solid fraction) is a predictor that is independent of tableting speed and can be used to predict tablet strength during formulation development and scale up.
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Improving Mechanical Properties of Caffeine and Methyl Gallate Crystals by Cocrystallization
Changquan Calvin Sun,Hao Hou +1 more
TL;DR: In this article, a 1:1 cocrystal of caffeine and methyl gallate was formed by suspending powders of the two pure compounds in ethanol, and the tabletability of the cocrestal was excellent over the entire pressure range.
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Compression behavior of orthorhombic paracetamol.
TL;DR: Compared to the monoclinic form, orthorhombic paracetamol is suitable for the direct compression process, and the crystalline structure accounts for its better compression behavior, because of the presence of sliding planes.
References
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Journal ArticleDOI
The tensile strength of lactose tablets.
John T. Fell,JM Newton +1 more
TL;DR: The behavioural depression after a 24 hr diet containing a-methytyrosine appears to be related to the brain levels of catecholamines, and although pheniprazine partially blocked the behavioural depression and noradrenaline depletion it did not alter plasma levels of a-methyltyrosines.
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Comments on an indirect tensile test on concrete cylinders
TL;DR: The tensile strength of concrete is measured by applying a compressive load to opposite generators of a cylindrical specimen as discussed by the authors, where the load is applied along the diametral plane containing the load.
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“Crushing-Strength” of Compressed Tablets I: Comparison of Testers
David B. Brook,Keith Marshall +1 more
TL;DR: In this article, the actual compressional load exerted at certain scale readings by four types of commercially available "crushing-strength" instruments has been determined by means of a piezo-electric force transducer.
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New instrument and method for evaluating tablet fracture resistance.
TL;DR: Results reported for 19 different tablets show that fracture resistance readings give smaller and more precise results than Strong Cobb hardness.