Journal ArticleDOI
Disseminated varioliform pustular eruption due to Mycobacterium avium intracellulare in an HIV-infected patient.
TLDR
This patient illustrates the wide spectrum of skin presentations that may be seen with mycohacterial infections in subjects infected with the human immunodeficiency virus (HIV).Abstract:
Severe disseminated infection due to Mycobacterium avium intracellulare, with unusual cutaneous features, is reported in a patient with acquired immunodeficiency syndrome (AIDS). The eruption appeared as disseminated pustular lesions which showed necrotic features and which led to varioliform scarring. Bacterial culture from the skin, blood, and bone marrow, and ultimately from the bronchoalveolar fluid and sputum, was positive for M. avium intracellulare. The patient was successfully treated using a multiple agent anti-mycobacterial regimen including clarithromycin, which appeared to be the most effective drug. This resulted in resolution of the cutaneous and general symptoms. Our patient illustrates the wide spectrum of skin presentations that may be seen with mycobacterial infections in subjects infected with the human immunodeficiency virus (HIV). Clarithromycin is an important agent for the treatment of these severe infections.read more
Citations
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Journal ArticleDOI
Familial cluster of cutaneous Mycobacterium avium infection resulting from use of a circulating, constantly heated bath water system
TL;DR: It is considered that this unusual familial cluster of cutaneous M. avium infection in healthy persons may have resulted from the use of contaminated bath water.
Journal ArticleDOI
Cutaneous infections associated with HIV/AIDS.
TL;DR: Although antiretroviral therapy has been helpful in relieving the burden of cutaneous infections in HIV-infected patients, it does not prevent all opportunistic infections in the skin and also has created new dilemmas.
Journal ArticleDOI
Cutaneous Mycobacterium avium intracellulare infection in an HIV+ patient mimicking histoid leprosy.
Alan S. Boyd,Jason B. Robbins +1 more
TL;DR: An AIDS patient with a cutaneous MAI infection that clinically and histopathologically mimicked histoid leprosy is reported, a presentation not previously described in this population.
References
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Journal ArticleDOI
Mycobacterium avium Complex Infections in Patients with the Acquired Immunodeficiency Syndrome
Catherine Hawkins,Jonathan W. M. Gold,Estella Whimbey,Timothy E. Kiehn,Patricia Brannon,Robert Cammarata,Arthur E. Brown,Donald Armstrong +7 more
TL;DR: Disseminated infection with Mycobacterium avium complex developed in 67 patients with the acquired immunodeficiency syndrome (AIDS) who were followed at Memorial Sloan-Kettering Cancer Center.
Journal ArticleDOI
Two Controlled Trials of Rifabutin Prophylaxis against Mycobacterium avium Complex Infection in AIDS
S D Nightingale,D. W. Cameron,Fred M. Gordin,Paul M. Sullam,David L. Cohn,Richard E. Chaisson,L J Eron,P D Sparti,B Bihari,D L Kaufman +9 more
TL;DR: Rifabutin, given prophylactically, reduces the frequency of disseminated M. avium complex infection in patients with AIDS and CD4 counts < or = 200 per cubic millimeter.
Journal ArticleDOI
Mycobacteria Other than Mycobacterium tuberculosis: Review of Microbiologic and Clinical Aspects
Gail L. Woods,John A. Washington +1 more
TL;DR: The rate of isolation of mycobacteria other than Mycobacterium tuberculosis (MOTT) has increased over the past several years; in some areas the isolation rate for Myc Cobacterium avium-Mycob bacterium intracellulare has surpassed that for M. tuberculosis.
Journal ArticleDOI
Clinical Trial of Clarithromycin for Cutaneous (Disseminated) Infection due to Mycobacterium chelonae
TL;DR: A multicenter clinical trial of the efficacy of single-drug therapy with clarithromycin for patients with cutaneous infection due to M. chelonae, especially in patients with disseminated infection.
Journal ArticleDOI
Mycobacterium avium Complex Infection and AIDS: Advances in Theory and Practice
TL;DR: This AIDS commentary reviews the current knowledge of MAC organisms and the clinical problems resulting from infection with these mycobacteria and develops new methods of managing this serious complication of advanced HIV-1 infection.
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Cutaneous Mycobacterium avium intracellulare infection in an HIV+ patient mimicking histoid leprosy.
Alan S. Boyd,Jason B. Robbins +1 more