Effect of Parkinson's disease-related alpha-synuclein abnormalities on the maturation of distinct iPSC-derived neuronal populations
Santivanez Perez,Jessica Andrea +1 more
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DissertationDOI
Investigating the effects of tau mutations in induced pluripotent stem cell-derived neurons
TL;DR: There was an increase in the proportion of neurons containing tau phosphorylated at the AT8 epitope in N279K cultures after 50 days, and more 4R tau was detected earlier in the N279k cultures than in controls, confirming the action of the N 279K mutation.
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DissertationDOI
Investigating the effects of tau mutations in induced pluripotent stem cell-derived neurons
TL;DR: There was an increase in the proportion of neurons containing tau phosphorylated at the AT8 epitope in N279K cultures after 50 days, and more 4R tau was detected earlier in the N279k cultures than in controls, confirming the action of the N 279K mutation.
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