Journal ArticleDOI
Effectiveness of antibacterial agents presently employed in ophthalmic preparations as preservatives against pseudomonas aeruginosa.
TLDR
Seven chemical substances or combinations of these substances presently employed as preservatives in ophthalmic solutions were studied to note their effectiveness as antibacterial agents against 13 different strains of Pseudomonas aeruginosa.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1963-10-01. It has received 34 citations till now. The article focuses on the topics: Antibacterial agent.read more
Citations
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Journal ArticleDOI
Cytotoxicity of Ophthalmic Preservatives
Journal ArticleDOI
Preservative-Free Artificial Tear Preparations: Assessment of Corneal Epithelial Toxic Effects
TL;DR: The results suggest that with frequent-dosage regimens, preservation-free artificial tear solutions-1 and -2 are free of the toxic effects associated with preserved solutions.
Journal ArticleDOI
Ocular preservatives: associated risks and newer options
TL;DR: Reasons for discontinuing traditional preservatives and the need for less-toxic molecules are discussed at length, along with newer options coming up in this area.
Journal ArticleDOI
Effects of copper and zinc ions on the germicidal properties of two popular pharmaceutical antiseptic agents cetylpyridinium chloride and povidone-iodine
J J Zeelie,T J McCarthy +1 more
TL;DR: The effects of copper and zinc ions on the rate of killing of Gram-negative bacterium Pseudomonas aeruginosa, Gram-positive bacterium Staphylococcus aureus and fungal yeast Candida albicans by antiseptic agents cetylpyridinium chloride and povidone-iodine (Betadine) were investigated.
Journal ArticleDOI
Relation between cation and lipid content of cell walls of Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella aerogenes and their sensitivity to polymyxin B and other antibacterial agents.
M. R. W. Brown,Sandra M. Wood +1 more
TL;DR: Sensitivity to polymyxin correlated with amount of phospholipid in wall fractions of Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella aerogenes and to a lesser extent with wall cation.
References
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Journal ArticleDOI
Practical laboratory test for the identification of Pseudomonas aeruginosa.
W. L. Gaby,C. Hadley +1 more
TL;DR: Preliminary experiments carried out in this laboratory indicated that while the cells of P. aeruginosa contain a peroxidase and catalase, other gram-negative bacilli similar to P.aeruginose contain similar enzymes which makes their utilization in a practical laboratory test extremely difficult.
Journal ArticleDOI
PREPARATION, STERILIZATION, AND PRESERVATION OF OPHTHALMIC SOLUTIONS: Experimental Studies and a Practical Method
TL;DR: It is demonstrated that simple, relatively inexpensive measures are sufficient to achieve accuracy of formulation and sterility of collyria, without sacrifice of drug stability or power of corneal penetration.
Journal ArticleDOI
Infection of the cornea with B. pyocyaneus. Clinical study and summary of ten cases personally observed.
TL;DR: Loss of the eye or loss of useful vision occurred in nineteen of the 23 reported since 1922 and the opportunity of observing, in epidemological form, several cases of corneal infection with B. pyocyaneus is rare.
Journal ArticleDOI
Origin and pathogenicity of pseudomonas pyocyanea in conjunctival sac
TL;DR: The "bacillus of blue pus" has been recognized for many years as a pathogenic agent capable of involving the eye and is described as attacking principally the corneal stroma.
Related Papers (5)
Effect of Ethylenediamine Tetraacetate on the Resistance of Pseudomonas aeruginosa to Antibacterial Agents
Growth of Pseudomonas aeruginosa in solutions of esters of p-hydroxybenzoic acid
W. B. Hugo,J. H. S. Foster +1 more