Journal ArticleDOI
Effects of nicotine on weight change and food consumption in rats.
Eileen McNair,Rebecca Bryson +1 more
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Overall tests indicated that nicotine withdrawal produced significant weight gains and nicotine administration produced inhibition of weight gain, and specific comparison tests showed these effects on food consumption and weight were strongest at the 0.6 level and that larger effects were obtained for males than for females.Abstract:
The present study was designed to test the effects of nicotine and nicotine withdrawal on weight change and food consumption in rats. Twelve male and 12 female three month old Sprague-Dawley rats were divided 3nto three treatment groups: 0.2, 0.4, and 0.6 mg nicotine/kg body wt. Half were given subcutaneous nicotine treatment for three weeks and then saline for three weeks; treatment sequence was reversed for the other half. Injections were administered three times daily throughout the experimental period. Prior to treatment, baseline measures were established for both food consumption and weight. Mean differences in weight change were calculated on a weekly basis throughout the experiment. Overall tests indicate that nicotine withdrawal produced significant (p<0.05) weight gains and nicotine administration produced inhibition of weight gain. A significant sex × drug × time interaction (p<0.05) demonstrated that food consumption increased when nicotine was discontinued and decreased when nicotine was administered. Specific comparison tests showed these effects on food consumption and weight were strongest at the 0.6 level and that larger effects were obtained for males than for females.read more
Citations
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Smoking, body weight, and their effects on smoking behavior: a comprehensive review of the literature
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Effects of Abstinence from Tobacco
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Effects of nicotine on body weight and food consumption in rats
TL;DR: The effects of nicotine on body weight, both during and after drug administration, were attenuated in comparison to the results of studies that provided sweet-tasting foods.
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Peculiar Vulnerability to Nicotine Oral Self-administration in Mice during Early Adolescence
TL;DR: A peculiar spontaneous drive toward oral nicotine consumption, as well as a nicotine-induced arousal, is specific to Early adolescence in mice, and the present animal model might be useful to investigate psychobiological determinants involved in early tobacco smoking in human adolescents.
References
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Changes associated with quitting cigarette smoking: the Framingham Study.
TL;DR: There were no significant differences at baseline between smokers who quit and smokers who continued smoking, and after quitting there was a short-term rise in weight for men and a beneficial impact on long-term vital capacity trends from quitting smoking.
Journal ArticleDOI
Metabolic changes associated with the cessation of cigarette smoking.
TL;DR: In this article, the authors observed before and one month after the cessation of smoking and found statistically significant increases in the body weight and body surface area while there were statistically significant decreases in the protein-bound iodine level.
Journal ArticleDOI
Obesity and smoking habits.
T. Khosla,C. R. Lowe +1 more
TL;DR: A large-scale survey of steel workers in South Wales has shown that ex-smokers who have given up smoking for more than eight years approach the body weight of men of the same age who have never smoked.
Journal ArticleDOI
Nicotine-induced weight loss in rats without an effect on appetite
Martin D. Schechter,P.G. Cook +1 more
TL;DR: The reduction in body weight after chronic nicotine administration proved highly replicable and was produced in the absence of a significant decrease in food consumption, and application to the human smoking habit is discussed.
Journal ArticleDOI
Variation in height and weight in the Norwegian population
TL;DR: For the men in the sample of Nor wegian-born residents of the United States and in the study groups in Norway additional data have been collected on dietary habits.