Journal ArticleDOI
Effects of polycythemia and anemia on cardiac output and other circulatory factors
TLDR
There was a significant decrease in total peripheral resistance in anemia and a marked rise in polycythemia, and the maximum number of red cells present for oxygen transport to the tissues was near the mean normal hematocrit of 40.Abstract:
Normovolemic anemia and polycythemia were studied in 14 dogs. Cardiac outputs increased with anemia and fell with rises in hematocrit. Although many factors—such as chemical changes—may play an important role in these variations in cardiac output, there was an indication that viscosity alone may have a major effect. There was no significant association between changes in cardiac output and the various pressures—mean arterial, mean right atrial, mean pulmonary and mean circulatory. Although the pressures did not change significantly, there was a significant decrease in total peripheral resistance in anemia and a marked rise in polycythemia. It was also found that the maximum number of red cells present for oxygen transport to the tissues was near the mean normal hematocrit of 40.read more
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Journal ArticleDOI
Direct relationship between blood pressure and blood viscosity in normal and hypertensive subjects: Role of fibrinogen and concentration
TL;DR: A direct correlation between blood pressure and blood viscosity among normotensive and hypertensive subjects is demonstrated, in part, due to the rheologic effects of an elevated fibrinogen level and to an increased hematocrit value.
Journal ArticleDOI
Oxygen transport in man.
Clement A. Finch,Claude Lenfant +1 more
TL;DR: OXYGEN transport is a corporate process involving several organs, each with its own regulatory system, and individual diseases of the heart, lungs or blood may impair the functional capacity of a singl...
Journal ArticleDOI
Sources of variation in haematocrit in birds
TL;DR: In temperate climates, haematocrit tended to be higher in winter than in summer, which may be due to dehydration or increased oxygen demand caused by thermogenesis, moult or acquisition of reproductive status.
Journal ArticleDOI
The Hemodynamic Response to Chronic Anemia
Martin Duke,Walter H. Abelmann +1 more
TL;DR: To determine whether the hyperkinetic circulatory response to chronic anemia is obligatory and to assess its strength and potential reversibility, the hemodynamic state at rest was assessed (indicator-dilution method) in 24 patients with Chronic anemia before and after certain interventions.
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