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Journal ArticleDOI

ENDOCARDITIS IN MAIN LINE OPIUM ADDICTS: Report on Eleven Cases

William F. Luttgens
- 01 Jun 1949 - 
- Vol. 83, Iss: 6, pp 653-664
TLDR
It is shown that venipuncture for the injection of opium or its derivatives was a possible factor in only 12 instances of cases of endocarditis reported in English in the past thirty years.
Abstract
THE possibility that intravenous injection of opium in addicts might serve as a means of entry for organisms that could cause endocarditis was suggested by Lutembacher 1 more than thirty years ago, when he wrote of " une injection intraveineuse malpropre ." A review of almost all the cases of endocarditis reported in English in the past thirty years, however, shows that venipuncture for the injection of opium or its derivatives was a possible factor in only 12 instances (table 1). An interesting group of 11 such cases, involving patients observed in a short period, forms the basis of this paper (table 2). METHOD OF ADMINISTRATION OF DRUG BY ADDICTS The method of administration of opium employed by addicts lends itself to the introduction of organisms into the blood stream. The equipment of an addict consists of an ordinary medicine dropper and a hypodermic needle, with a bit of cigaret paper

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Citations
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Journal ArticleDOI

Infective endocarditis in the antibiotic era.

TL;DR: Clinical Course of Treated Endocarditis Fever The institution of appropriate antibiotic therapy frequently leads to defervescence and increase in the sense of well-being within several days.
Journal ArticleDOI

Effect of morphine on resistance to infection.

TL;DR: The results suggest that there is a close relationship between the fact that morphine exacerbates infections and thefact that morphine depresses phagocytic functions, and the negative effect of morphine onphagocytosis is at least one of the reasons for its negative effect on the development of infections.
Journal ArticleDOI

The narcotic addict as a medical patient

TL;DR: Narcotic addicts present with many physical findings and disease patterns that are relatively unusual and many obscure issues could profitably be investigated with the use of modern technics of clinical research.
Journal Article

Morphine Enhances Macrophage Apoptosis

TL;DR: The present study provides a basis for a hypothesis that morphine may be directly compromising immune function by promoting Mphi apoptosis in patients with opiate addiction.
Journal ArticleDOI

Right-sided valvular infective endocarditis: A clinicopathologic study of twelve necropsy patients

TL;DR: The infective endocarditis in each of the nine patients with alcoholism or heroin addiction and in the one with congenital heart disease was primary in the heart; in the remaining two patients, it was secondary to generalized infection affecting many body organs.
References
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Journal ArticleDOI

Subacute endocarditis and systemic mycosis (monilia)

Henry Joachim, +1 more
- 20 Jul 1940 - 
TL;DR: The case of F. M., a white man aged 48, American born, married, a bookkeeper, was admitted to the surgical service of the Cumberland Hospital on April 24, 1939, because of midabdominal pain of two and was considered worthy of publication.
Journal ArticleDOI

Mycotic Endocarditis : Report of a Case.

TL;DR: The following case, in a drug addict, is similar in many respects to that of Joachim and Polayes and is considered worthy of reporting because of its apparent rarity, andBecause of its possible public health importance, since these cases occurred in drug addicts.
Journal ArticleDOI

Malaria in narcotic addicts

J. C. Geiger
- 23 Apr 1932 - 
TL;DR: The unusual presence of six cases of malaria at one time in the San Francisco Hospital led to an investigation to determine the source of infection and the accuracy of the department's investigation is plainly manifest.
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