Book ChapterDOI
Forcing a Sequential Experiment to be Balanced
Herman Chernoff
- pp 15-31
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The article was published on 2008-01-01. It has received 75 citations till now. The article focuses on the topics: Forcing (recursion theory).read more
Citations
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Journal ArticleDOI
Improper analysis of trials randomised using stratified blocks or minimisation.
Brennan C Kahan,Tim P. Morris +1 more
TL;DR: It is shown that balancing treatment groups using stratification leads to correlation between the treatment groups, and if this correlation is ignored and an unadjusted analysis is performed, standard errors for the treatment effect will be biased upwards, resulting in 95% confidence intervals that areToo wide, type I error rates that are too low and a reduction in power.
Journal ArticleDOI
Handling Covariates in the Design of Clinical Trials.
TL;DR: A new class of procedures, covariate-adjusted response adaptive (CARA) randomization procedures that attempt to optimize both efficiency and ethical considerations, while maintaining randomization are advocated.
Journal ArticleDOI
Asymptotic properties of covariate-adjusted response-adaptive designs
TL;DR: In this article, a framework for covariate-adjusted response-adaptive (CARA) designs is proposed for the allocation of subjects to K (≥ 2) treatments.
Journal ArticleDOI
A Randomised Controlled Comparison of Second-Level Treatment Approaches for Treatment-Resistant Adults with Bulimia Nervosa and Binge Eating Disorder: Assessing the Benefits of Virtual Reality Cue Exposure Therapy
Marta Ferrer-García,José Gutiérrez-Maldonado,Joana Pla-Sanjuanelo,Ferran Vilalta-Abella,Giuseppe Riva,Massimo Clerici,Joan Ribas-Sabaté,Alexis Andreu-Gracia,Fernando Fernández-Aranda,Laura Forcano,Nadine Riesco,Isabel Sánchez,Neli Escandón-Nagel,Osane Gomez-Tricio,Virginia Tena,Antonios Dakanalis,Antonios Dakanalis +16 more
TL;DR: The effectiveness of virtual reality-CET as a second-level treatment strategy for 64 patients with bulimia nervosa and binge eating disorder who had been treated with limited results after using a structured CBT programme, in comparison with A-CBT was assessed.
Journal ArticleDOI
Generalized method for adaptive randomization in clinical trials
TL;DR: The paper lists the desirable characteristics of allocation methods and shows that the proposed method fulfils the majority and is easy to use in the clinical context, once the coding has been established.
References
More filters
Journal ArticleDOI
Improper analysis of trials randomised using stratified blocks or minimisation.
Brennan C Kahan,Tim P. Morris +1 more
TL;DR: It is shown that balancing treatment groups using stratification leads to correlation between the treatment groups, and if this correlation is ignored and an unadjusted analysis is performed, standard errors for the treatment effect will be biased upwards, resulting in 95% confidence intervals that areToo wide, type I error rates that are too low and a reduction in power.
Journal ArticleDOI
Rerandomization to improve covariate balance in experiments
Kari Lock Morgan,Donald B. Rubin +1 more
TL;DR: In this article, the authors show that covariate data are available before units are exposed to treatments and can be used to check covariate balance before the physical experiment takes place, provided a precise definition of imbalance has been specified.
Journal ArticleDOI
Handling Covariates in the Design of Clinical Trials.
TL;DR: A new class of procedures, covariate-adjusted response adaptive (CARA) randomization procedures that attempt to optimize both efficiency and ethical considerations, while maintaining randomization are advocated.
fMRI of Emotion Regulation of Negative Self-Beliefs
TL;DR: Meditation practice was associated with decreases in negative emotion and social anxiety symptom severity, and increases in attention-related parietal cortex neural responses when implementing attention regulation of negative self-beliefs.
Journal ArticleDOI
A Randomised Controlled Comparison of Second-Level Treatment Approaches for Treatment-Resistant Adults with Bulimia Nervosa and Binge Eating Disorder: Assessing the Benefits of Virtual Reality Cue Exposure Therapy
Marta Ferrer-García,José Gutiérrez-Maldonado,Joana Pla-Sanjuanelo,Ferran Vilalta-Abella,Giuseppe Riva,Massimo Clerici,Joan Ribas-Sabaté,Alexis Andreu-Gracia,Fernando Fernández-Aranda,Laura Forcano,Nadine Riesco,Isabel Sánchez,Neli Escandón-Nagel,Osane Gomez-Tricio,Virginia Tena,Antonios Dakanalis,Antonios Dakanalis +16 more
TL;DR: The effectiveness of virtual reality-CET as a second-level treatment strategy for 64 patients with bulimia nervosa and binge eating disorder who had been treated with limited results after using a structured CBT programme, in comparison with A-CBT was assessed.