Journal ArticleDOI
Functional Characteristics of Mast Cells Associated With Rat Mammary Tumors Induced by 7,12-Dimethylbenz[a]anthracene
John W. Combs,Dallas M. Purnell +1 more
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This article is published in Journal of the National Cancer Institute.The article was published on 1973-04-01. It has received 11 citations till now. The article focuses on the topics: 7,12-Dimethylbenz[a]anthracene & Mast cell.read more
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Journal ArticleDOI
Mast cell-mediated tumor-cell cytotoxicity. Role of the peroxidase system.
TL;DR: A sequence of reactions is proposed in which mast cells, stimulated to release their granules by H2O2 generated by adjacent phagocytes, react with H2 O2 and a halide to damage tumor cells.
Journal ArticleDOI
Sequential mast cell infiltration and degranulation during experimental carcinogenesis.
TL;DR: There is a positive correlation between developing carcinomas and mast cell density in hamster buccal pouches undergoing chemically induced carcinogenesis, and observed processes of upward migration and degranulation continued progressively during the 12- and 14-week periods of DMBA application in correlation with the progression of the tumor.
BookDOI
Local invasion and spread of cancer
TL;DR: A comparison of the progression of selected, topographically particular, tumors in the head and neck region and the results show neoplastic progression of the myeloid leukemias is compared.
Journal ArticleDOI
The nature and significance of tumour-associated mast cells.
TL;DR: The role of the mast cell in tumour growth was examined in the rat with the use of a transplanted sarcoma and the addition of mast cells to the initial tumour inoculum and by pharmacological inhibition of mast cell degranulation was demonstrated.
Book ChapterDOI
The mast cells.
L. Enerbäck,K. Norrby +1 more
TL;DR: Two characteristic property of the mast cells are their content of receptors with high affinity for IgE and histamine, which are the main repository for this amine in mammalian tissues.