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Journal ArticleDOI

Further observations on amphiphil cells in the pancreatic islets.

August Epple
- 01 Oct 1967 - 
- Vol. 9, Iss: 2, pp 137-142
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TLDR
It is clear that the specifity of the pseudoisocyanine method for islet insulin detection deserves further investigations, and the possibility is discussed that the amphiphil contain two hormones and that amphiphils in the toad represent transformations from D- to B-cells.
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This article is published in General and Comparative Endocrinology.The article was published on 1967-10-01. It has received 15 citations till now. The article focuses on the topics: Scyliorhinus canicula & Bufo.

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Citations
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Journal ArticleDOI

Comparison of some hormonal effects on carbohydrate metabolism in an elasmobranch (Squalus acanthias) and a holocephalan (Hydrolagus colliei)

TL;DR: The abundance of lipid, in contrast to the sparse glycogen deposits, in both dogfish and ratfish liver (70% and 80% of wet weight), implies that lipid reserves may be of more fundamental physiologic importance to these fishes.
Journal ArticleDOI

Ontogenetic and Phylogenetic Development of the Endocrine Pancreas (Islet Organ) in Fishes

TL;DR: There are now several markers of cell differentiation in the mammalian endocrine pancreas which would be useful for investigating the development of the islet organ and cells of the remaining GEP system in fish.
Journal ArticleDOI

The organization of the endocrine pancreas: a hypothetical unifying view of the phylogenetic differences.

TL;DR: Higher nonmammalian vertebrates are readily encompassed by this hypothesis and mammals may be included as well, and these concepts may have important implications for the understanding of the mammalian pancreas.
Journal ArticleDOI

Light- and electron-microscopic studies of the pancreatic islet cells in the chicken under normal and experimental conditions.

TL;DR: Light- and electron-microscopic observations were made on the alpha, beta and delta cells of the pancreatic islets of the domestic fowl and on their cytologic changes following the administration of glucose, glucagon, insulin, alloxan and carbutamide.
Book ChapterDOI

5 - The Endocrine Pancreas

August Epple
- 01 Jan 1969 - 
TL;DR: This chapter discusses the evolution and functions of islet hormone in fishes and highlights four types of pancreas: a cyclostome type with total separation of specialized exocrine and endocrine tissue, a primitive gnathostometype, where the ductlike arrangement of theendocrine tissue resembles the early stages of human islet formation, and a tetrapodlike type of more or less compact pancrea with typical islet.
References
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Journal ArticleDOI

Über den Nachweis von Insulin mit den metachromatisch reagierenden Pseudoisocyaninen

TL;DR: In this article, Granula, die with Pseudoisocyanininfarbstoffen nach Oxydation metachromatisch reagieren, are found in the Brockmannschen Korperchen der Schleie.
Journal ArticleDOI

The islets of Langerhans in ducks and chickens with special reference to the argyrophil reaction.

TL;DR: The pancreas of birds is a suitable object for studying the A and B cells separately, since the two cell systems are topografically almost entirely segregated in the form of light and dark islets of Langerhans.
Journal ArticleDOI

A Staining Sequence for A, B and D Cells of Pancreatic Islets

TL;DR: Difficulties in embedding compact pancreatic tissue can be overcome by dehydrating to 80% ethanol, followed by tetrahydrofurane as the intermediate fluid to paraffin infiltration.
Journal ArticleDOI

The cell types in the endocrine pancreas of the human fetus

TL;DR: The development of phosphatase and esterase activities in the islets seemed far from complete, when morphologically differentiated islet cells could be recognized.
Journal ArticleDOI

On the nature of the metachromatic cells of pancreatic islets

TL;DR: It is suggested that the islet argyrophil-metachromatic cells (A1-cells of Swedish Authors) are identical with D-cells and very likely represent a morphologically and functionally indipendent cell type.
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