scispace - formally typeset
Open AccessJournal Article

Generalized morphea with blisters. A case report.

TLDR
A patient suffering from generalized morphea developed blisters in the morpheic plaques on her buttocks, which had an increased concentration of serum aminoterminal propertice of type III procollagen, an echo response and thickened skin on ultrasound scanning, and compact bundles of collagen fibrils with bimodal distribution of the diameters.
Abstract
A patient suffering from generalized morphea developed blisters in the morpheic plaques on her buttocks. The plaques had an increased concentration of serum aminoterminal propertice of type III procollagen, an echo response and thickened skin on ultrasound scanning, and compact bundles of collagen fibrils with bimodal distribution of the diameters. The blisters appeared as an echo-free band in the subepidermal zone by ultrasound scanning. Electron microscopy revealed blisters in the upper papillary dermis, surrounded by degraded collagen fibrils.

read more

Citations
More filters
Journal ArticleDOI

High frequency, high resolution B-scan ultrasound in the assessment of skin tumours.

TL;DR: B‐scanning is a reliable non‐invasive method for assessing tumour dimensions, and has potential for the study of tumour characteristics for diagnostic purposes, and results for dermatofibroma were atypical, due to paradoxical low internal echogenicity and increased echo absorption.
Journal ArticleDOI

Bullous morphea: Clinical, pathologic, and immunopathologic evaluation of thirteen cases

TL;DR: The results suggest that the pathogenesis of bullous morphea is related to lymphatic dilatation as well as release of major basic protein from eosinophils in some patients.
Journal ArticleDOI

Bullous lesions in scleroderma.

TL;DR: Three histologic patterns have been reported: lichen sclerosus et atrophicus‐like, lymphangiectatic blisters and autoimmune blistering diseases, which all suggest bullous lesions in localized or systemic scleroderma.
Journal ArticleDOI

Intertriginous bullous morphea: A clue for the pathogenesis?

TL;DR: A 69-year-old woman presented with a history of generalized morphea diagnosed 9 years earlier; and a 1-month history of pruritic bullae on her inframammary folds, axillary regions, lower abdomen, upper extremities and inguinal folds, where the diagnosis of bullous morphea was established.
Journal ArticleDOI

Three cases of bullous morphea: histopathologic findings with implications regarding pathogenesis

TL;DR: All of the cases of bullous morphea showed hemorrhagic content in the bullae, which suggests local trauma as a mechanism involved in bulla formation.
References
More filters
Journal ArticleDOI

Herpetiform pemphigus induced by penicillamine.

TL;DR: A patient with arthritis is described who developed a dermatitis herpetiformis‐like rash after 8 months of D‐penicillamine therapy and which cleared soon after the drug was discontinued.
Journal Article

Serum aminoterminal propeptide of type III procollagen in progressive systemic sclerosis and localized scleroderma.

TL;DR: In patients with acrosclerosis, elevated PIIINP seems to be correlated to rapid progression and extension of lesions, while the present investigation did not allow judgement of effects of treatment with either penicillamine or cyclosporin A.
Related Papers (5)