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Histopathological pattern of endometrial samples in abnormal uterine bleeding

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TLDR
It is important to know the histological pattern of the endometrium in abnormal uterine bleeding in different age groups since it will help in the management of the cases, and studying the histopathological pattern is to help in correctly managing the cases.
Abstract
Background: Histological characteristics of endometrial biopsy material as assessed by light microscopy remain the diagnostic standard for the clinical diagnosis of endometrial pathology. Management of abnormal uterine bleeding is not complete without tissue diagnosis. The aim of the study was to find out the histopathological pattern of the endometrium in abnormal uterine bleeding. Materials and Methods: Endometrial biopsy specimens received from Jan 2007 to Nov 2010 were studied retrospectively in the Department of Histopathology, Helping Hands Community Hospital, Kathmandu. The specimens were routinely processed and the hematoxyllin and eosin stained slides were studied. Results: A total of 300 specimens were analyzed. In the group of patients less than 40 years of age, 73 (50%) were normal, 34(23%) had abnormal physiologic changes and 13 (9%) had pregnancy related complications and benign changes. In the age group between 40 – 55 years, abnormal physiological changes, benign conditions and normal physiological changes were 45 (32%), 41 (29%) and 37 (26%) respectively. In the age group > 55 years, there were 3(21%) malignant and 3(21%) benign conditions. There were 5(36%) unsatisfactory samples in this age group. Conclusion: It is important to know the histological pattern of the endometrium in abnormal uterine bleeding in different age groups since it will help in the management of the cases. In this study endometrial hyperplasias were seen in 55 cases (18.8%). The importance of studying the histological pattern of endometrium in abnormal uterine bleeding in different age group is to help in correctly managing the cases. Keywords: Endometrium; Simple hyperplasia; Complex hyperplasia; Endometritis; Endometrial Carcinoma. DOI: 10.3126/jpn.v1i1.4443 Journal of Pathology of Nepal (2011) Vol.1, 13-16

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Abnormal Uterine Bleeding: a Histopathological Study

TL;DR: The types and frequencies of pathologies in endometrial curettings of abnormal uterine bleeding were determined & differentendometrial pathology in patient to age groups were compared to compare different endometrians in patient and age groups.
Journal ArticleDOI

Histopathological patterns of endometrial lesions in patients with abnormal uterine bleeding in a cosmopolitan population

TL;DR: The frequency and histological types and patterns of the endometrial lesions in patients with abnormal uterine bleeding (AUB) in private practice in Benin-City, Nigeria are highlighted and product of conception was the most commonly encountered among reproductive women.
Journal Article

Clinco-Pathological Patterns in Women with Dysfunctional Uterine Bleeding

TL;DR: DUB occurs secondary to a wide variety of functional and structural abnormalities, warranting a thorough evaluation especially in perimenoupausal females, and significant number of endometrial samples revealed pathology renderingendometrial curetting and biopsy an important procedure.
Journal ArticleDOI

A two year histopathological study of endometrial biopsies in a teaching hospital in Northern India

TL;DR: The most common finding in patients of infertility was proliferative endometrium indicating anovulatory cycles, and Endometrial biopsy is a valuable tool in assessment of endometrial status in infertility, as well as benign and malignant pathology in abnormal uterine bleeding due to relative ease of procedure and rapid availability of results.
Journal ArticleDOI

A Study on Histopathological Patterns of Endometrium in Different Types of Abnormal Uterine Bleeding Among Peri And Postmenopausal Women

TL;DR: Histopathological evaluation of endometrial samples is especially indicated in peri and postmenopausal women to rule out neoplastic and preneoplastic conditions.
References
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Journal ArticleDOI

Endometrial histopathology in patients with culture-proved upper genital tract infection and laparoscopically diagnosed acute salpingitis.

TL;DR: Endometrial biopsy specimens from 69 consecutive patients with clinically suspected acute pelvic inflammatory disease who underwent microbiological evaluation for UGTI and laparoscopically confirmed acute salpingitis were studied to define and quantitate histologic changes in the endometrium that best correlate with documented upper genital tract infection (UGTI).
Journal ArticleDOI

Hormonal pathology of the endometrium.

TL;DR: The histologic patterns encountered in the most commonly used hormone therapies: oral contraceptives, ovulation stimulation, hormone replacement therapy, and antitumoral hormone therapy are described.
Journal ArticleDOI

Endometrial morphology in asymptomatic postmenopausal women

TL;DR: It is concluded that the yield for neoplasia is so low that screening endometrial biopsy is not justified in asymptomatic perimenopausal and postmenopausal women.
Journal ArticleDOI

Benign endometrial hyperplasia sequence and endometrial intraepithelial neoplasia.

TL;DR: The use of an internal standard for cytology assessment, combined with the distinctive topography of a clonal process, enables the diagnosis of EIN lesions with a long-term cancer risk 45-fold greater than that of their benign endometrial hyperplasia counterparts.
Book ChapterDOI

Anatomy and Histology of the Uterine Corpus

Alex Ferenczy
TL;DR: Development of histology and microscopy led to an explosive growth of knowledge of the uterus, with detailed descriptions of the embryology by Muller in the 19th century and hormone-mediated cyclic endometrial changes by Hitschmann and Adler and later by Robert Schroeder in the early 20th century.
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