Open AccessJournal Article
Hypothalamic encephalitis with oligodendrocytic glial nodules. Case report of a Chinese boy.
Luning Wang,Huang Kw +1 more
TLDR
Autopsy revealed severe bilateral outfall of neurons in the ventromedian hypothalamic nuclei with diffuse hyperplasia of astrocytes and some glial nodules consisting chiefly of oligodendroglias and perivascular cuffing, providing significant data for the study of hypothalamic function.Abstract:
A case of hypothalamic encephalitis proved by postmortem examination is reported. The patient was a three-year-old Chinese boy who had complained of obesity for one year and fever for half a year. Three days after admission to a hospital, the patient suddenly died of allergic reaction to intramuscular penicillin, without additional complaints. Autopsy revealed severe bilateral outfall of neurons in the ventromedian hypothalamic nuclei with diffuse hyperplasia of astrocytes and some glial nodules consisting chiefly of oligodendroglias and perivascular cuffing. Similar changes were noticed in hypothalamus at the level of optic chiasm, but the posterior hypothalamic nuclei and lateral hypothalamic nuclei were intact. This article provides significant data for the study of hypothalamic function.read more
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Book ChapterDOI
The human hypothalamus in metabolic and episodic disorders.
TL;DR: There is frequent hypothalamic comorbidity in terms of mood, sleep and rhythm disorders due to the intense hypothalamic interconnectivity and integrative mechanisms in disorders of eating and metabolism.
Journal ArticleDOI
Hypothalamic Encephalitis with Bradycardia
Shozo Ishikawa,Hajime Aoki,Chiho Akahane,Hirohide Shimada,Yo-ichi Takei,Yoshiki Ichinose,Shu-ichi Ikeda +6 more
TL;DR: The results of endocrine tests were compatible with hypothalamic insufficiency with partial hypopituitarism and the syndrome of inappropriate secretion of ADH.