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Incorporação de atores da Rede Brasileira de Pesquisa em TB nas atividades do Jornal Brasileiro de Pneumologia da Sociedade Brasileira de Pneumologia e Tisiologia

Afrânio Lineu Kritski
- 01 Aug 2004 - 
- Vol. 30, Iss: 4, pp 303-306
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TLDR
This issue of the Jornal Brasileiro dePneumonologia (JBP, Brazilian Journal of Pulmonary Medicine) is a collection of articles concerning tuberculosis (TB), conceived as a companion to the publication of the proceedings and conclusions of the I Encontro Nacional deTuberculose (1st National Tuberculosis Forum), to be held in Brasilia from June 30 to July 3, 2004.
Abstract
This issue of the Jornal Brasileiro dePneumonologia (JBP, Brazilian Journal ofPulmonary Medicine) is a collection of articlesregarding tuberculosis (TB). It was conceived as acompanion to the publication of the proceedingsand conclusions of the I Encontro Nacional deTuberculose (1st National Tuberculosis Forum), tobe held in Brasilia from June 30 to July 3, 2004.The forum represents a milestone in the history ofPhthisiology in Brazil and is the culmination ofefforts by the think tank known as the InteligenciaNacional em TB (National TB Knowledge Base),which is composed of representatives of variousentities. The Secretaria de Vigilancia em Saude doMinisterio da Saude (Ministry of Health, Departmentof Health Oversight), the Sociedade Brasileira dePulmonologia e Tisiologia (SBPT, Brazilian Societyof Pulmonology and Phthisiology) and the RedeBrasileira de Pesquisa em Tuberculose (Rede-TB,Brazilian Tuberculosis Research Network) are allrepresented. The impact of their actions, agreedupon in a transparent and cordial way, can be seenas much in the content of the event as in thenature of the articles published in this issue of thejournal. These articles provide unequivocal evidenceof the interdisciplinary and horizontal quality ofRede-TB activities. When the position of JPBassociate editor for TB was created, there were onlytwo TB-related articles under review. On May 14,2004, Rede-TB researchers were invited, and readilyagreed, to work in collaboration with the JBP. Sincethen, 20 original articles, 3 review articles and 2case reports have been submitted for publication.These 25 articles address various spheres ofknowledge: epidemiology (4), diagnosis (6), clinicalmedicine and treatment (7), operational research(4), molecular epidemiology (1), genetics (1),immunology(1) and chemoprophylaxis(1). Thereviewers should be complimented on their agility,which made it possible to have a sufficient numberof TB-related articles approved for publicationbefore the deadline for this issue. Although it wasnot possible, in the current issue, to publish all ofthe TB-related manuscripts submitted, many ofthese extremely relevant and high-quality articleswill appear in subsequent issues of the JBP.In response to a joint proposal put forth bythe governmental projects Polos de EducacaoPermanente (Poles of Continuing Education) andParque Produtivo (Productivity Estate), a re-evaluation of the functions and interrelationshipsamong the various entities affecting TB control iscurrently underway. This re-assessment involves thefederal Ministries of Health, Science andTechnology, and Education, as well as public andprivate medical schools. In addition, state andmunicipal administrations, health councils, medicalsocieties such as the SBPT, professionalorganizations such as the Conselho Regional deMedicina do Rio de Janeiro (CREMERJ) andnongovernmental organizations dealing with TBor HIV, as well as research networks such as theRede-TB, were included in this project. Conferenceshave been held on the subjects of scientifictechnology and technological innovation, theaccreditation status of university hospitals has beenscrutinized, and the subject of university reformhas been discussed in depth. The Rede-TBresearchers have been working in cooperation withthe SBPT, using the JBP as a communicationvehicle. Their objectives are to identifyshortcomings and challenges yet to be met in thefields of science, technology and technologicalinnovation, propose directives that encourage the

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References
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Limitações do uso do fragmento mtp40 como marcador de diferenciação entre Mycobacterium tuberculosis e M. bovis

TL;DR: Os bacilos que causam a tuberculose estaoagrupados no complexo Mycobacteriumtuberculosis, composto por: M. bovis, M. africanum e M. canettii, uma variante de M. tuberculosis encontrada na regiao da Somalia.
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Ocorrência de tuberculose doença entre contatos de tuberculose sensível e multirresistente

TL;DR: Os resultados deste estudo sugerem that a ocorrencia de tratamentos de tuberculose gerados entre contatos intra-domiciliares of tuberculos sensivel e tuberculoses multirresistente e semelhante e ocorreu micro-epidemia de tuberclesistente confirmada por teste of sensibilidade em oito familias.
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É possível uma vacina gênica auxiliar no controle da tuberculose

TL;DR: The protein (hsp65) as discussed by the authors was developed to induce the secretion of Th1 cytokines, such as gamma-interferon, associated with disease control and stimulate cytotoxic CD8 and CD4 T-cell clones that can be characterized as memory cells.