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Journal ArticleDOI

Inflammatory reaction after intrasynovial injection of microcrystalline adrenocorticosteroid esters.

Daniel J. McCarty, +1 more
- 01 Aug 1964 - 
- Vol. 7, Iss: 4, pp 359-367
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TLDR
Injection of commercially available microcrystalline adrenocorticosteroid esters into normal canine joints was ac-companied by a leukocyte-rich exudative response, roughly proportional to the dose injected, and no tenderness or evidence of pain was noted.
Abstract
Injection of commercially available microcrystalline adrenocorticosteroid esters into normal canine joints was ac-companied by a leukocyte-rich exudative response, roughly proportional to the dose injected. No tenderness or evidence of pain was noted. Injection of these preparations into normal human joints often induced similar reactions which were sometimes painful. The response varied with the preparation employed and in the case of hydrocortisone acetate, with the manufacturer of the drug. The possible injurious effects of this relatively painless inflammatory response are discussed.

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Citations
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Long-term analysis of patients having surgical treatment for carpal tunnel syndrome.

TL;DR: Steroids were least effective in hands that had muscle involvement, and 15 of the 40 hands with muscle involvement regained their muscle mass by the time of the final examination.
Journal ArticleDOI

Intra-articular corticosteroids : Guide to selection and indications for use

Jacques R. Caldwell
- 01 Oct 1996 - 
TL;DR: A literature review suggests that judicious use of intra- and periarticular corticosteroids is very helpful in temporarily reducing pain and inflammation in musculoskeletal structures and may facilitate increased motion and function in selected cases.
Journal ArticleDOI

Arthritis Associated with Apatite Crystals

TL;DR: Experimental injection of hydroxyapatite crystals into dog knee joints produces inflammation supporting the potential role for these crystals in joint disease.
References
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Journal ArticleDOI

The Significance of Calcium Phosphate Crystals in the Synovial Fluid of Arthritic Patients: The Pseudogout Syndrome: I. Clinical Aspects

TL;DR: In this article, the authors examined over 200 consecutive specimens of synovial fluid with phase contrast and polarized light microscopy and obtained a collection of fluids from seven patients from seven different patients.
Journal Article

The Significance of Calcium Phosphate Crystals in the Synovial Fluid of Arthritic Patients: The "Pseudogout Syndrome"

TL;DR: Excerpt In the course of examining over 200 consecutive specimens of synovial fluid with phase contrast and polarized light microscopy, a collection of fluids from seven patients was obtained and it was found that some of the fluids obtained belonged to the central nervous system.
Journal ArticleDOI

Hydrocortisone and cortisone injected into arthritic joints; comparative effects of and use of hydrocortisone as a local antiarthritic agent.

TL;DR: The antirheumatic effect of cortisone administered parenterally or orally has been documented in numerous reports during the past two years, but little has been written about cortis one administered locally into the arthritic joint.
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