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Journal ArticleDOI

Interval breast cancers in the screening mammography program of British Columbia : analysis and classification

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TLDR
The availability of a population-based cancer registry in the province of British Columbia makes an accurate determination of interval cancers and sensitivity rates possible and these data are essential for quality analysis, program planning, and education of radiologists in screening mammography.
Abstract
Interval cancers in an annual mammography screening program are defined as cancers detected within 12 months after a mammographic screening in which findings are considered normal. Our objective was to analyze interval cancers for histologic type, tumor size, staging, and histologic grade. A classification for interval cancers is presented. Detection of interval cancers is an integral part of quality control and is required for the establishment of sensitivity rates for screening mammography, a necessary part of implementing the recommendations for breast cancer screening.A total of 47,583 mammographic screening examinations of 38,219 women were available for review for the period of July 1988 to March 1991. Linkage with the provincial population-based cancer registry provided identification of all interval cancers of the breast. Histologic analysis of breast cancers was provided by an internationally recognized breast cancer pathologist who interpreted the specimens twice.A total of 207 breast cancers we...

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Journal ArticleDOI

Diagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancer.

TL;DR: In nonfatty breasts, US and MR imaging were more sensitive than mammography for invasive cancer, but both MR imaging and US involved risk of overestimation of tumor extent.
Journal ArticleDOI

Recommendations for follow-up care of individuals with an inherited predisposition to Cancer. II. BRCA1 and BRCA2

TL;DR: It is recommended that individuals considering genetic testing be counseled regarding the unknown efficacy of measures to reduce risk and that care for individuals with cancer-predisposing mutations be provided whenever possible within the context of research protocols designed to evaluate clinical outcomes.
Journal ArticleDOI

Breast Density as a Predictor of Mammographic Detection: Comparison of Interval- and Screen-Detected Cancers

TL;DR: Mammographic breast density appears to be a major risk factor for interval cancer in women participating in mammographic screening from 1988 through 1993.
Journal ArticleDOI

Effect of Age, Breast Density, and Family History on the Sensitivity of First Screening Mammography

TL;DR: The sensitivity of modern mammography is highest among women aged 50 years and older who have primarily fatty breast density and particularly low when the time between screenings is about 2 years or when women have a family history of breast cancer.
References
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Journal ArticleDOI

Evidence on screening for breast cancer from a randomized trial.

TL;DR: Based on current findings in the HIP study, there appears to be strong support for periodic screening at ages 50 years and over with clinical examination and mammography; to justify screening under 50, new information from other studies is required.
Journal ArticleDOI

What is the optimum interval between mammographic screening examinations? An analysis based on the latest results of the Swedish two-county breast cancer screening trial.

TL;DR: The reduction in the rate of advanced cancers and of breast cancer mortality in the group allocated to screening when compared to the control group has accelerated with a further year of follow-up, and the implications for screening policy, including the interscreening interval are discussed.
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Survival experience in the breast cancer detection demonstration project

TL;DR: Very high survival rates have been observed in four through 11 years of follow‐up in 4,240 women with a histologically confirmed diagnosis of breast cancer in the Breast Cancer Detection Demonstration Project (BCDDP).
Journal ArticleDOI

Medical audit of a rapid-throughput mammography screening practice: methodology and results of 27,114 examinations.

TL;DR: Medical audit results from the entire experience of a rapid-throughput mammography screening practice are presented, comprising 27,114 examinations conducted from April 1985 to September 1989, and screened a self-selected physician-referred population, almost 94% of whom were asymptomatic.
Journal ArticleDOI

Interval carcinomas in the Malmö Mammographic Screening Trial: radiographic appearance and prognostic considerations.

TL;DR: Interval carcinomas in this series were dominated by comedo, medullary, and mucinous carcinomas that often had a nonspecific appearance on prior screening mammograms and contained a subset of rapidly growing tumors with a grave prognosis.
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