Journal ArticleDOI
Isolation of (-)-Epicatechin from Pterocarpus marsupium and its Pharmacological Actions
B K Chakravarthy,K D Gode +1 more
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TLDR
(-)-epicatechin did not have any effect on central nervous system of rats and mice, but had shown both positive chronotropic and inotropic effects on frog hearts, the effect of which is blocked by propranolol.Abstract:
(-)-Epicatechin has been isolated from the bark of PTEROCARPUS MARSUPIUM Roxb (Leguminosae). This flavonoid compound was tested for its activity on central nervous system, isolated frog heart preparations and blood sugar levels of rats. Preliminary acute toxicity studies were also carried out. It was observed that (-)-epicatechin did not have any effect on central nervous system of rats and mice, (-)-epicatechin had shown both positive chronotropic and inotropic effects on frog hearts, the effect of which is blocked by propranolol. The compound in higher doses caused hyperglycemia in rats and this effect is also blocked by propranolol, showing adrenergic type of activity. (-)-Epicatechin was found to have no untoward effect even in higher doses.read more
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Journal ArticleDOI
Two aurone glycosides from heartwood of Pterocarpus santalinus.
TL;DR: Two new aurone glycosides, 6 hydroxy 5 methyl 3',4',5' trimethoxy aurone 4-O-alpha-L-rhamnopyranoside and 6,4' dihydroxy aur one 4- O-rutinoside have been isolated from the ethanolic extract of the wood of Pterocarpus santalinus.
Book ChapterDOI
Reactions at the Interflavanoid Bond of Proanthocyanidins
TL;DR: Condensed tannins with a 5,7-dihydroxy A-ring are particularly susceptible to interflavanoid bond cleavage under either acidic or basic condi-tions as discussed by the authors.
Journal ArticleDOI
Plants and Plant Products with Potential Anticonvulsant Activity – A Review
TL;DR: The present review emphasizes pharmacological reports on anticonvulsant plants, plant products and formulations and various chemical constituents isolated from different plants responsible for anticonVulsant activity and their possible mechanism of actions have been incorporated.
Journal Article
Pterocarpus marsupium Roxb. - a comprehensive review.
TL;DR: The present review explores the description, traditional uses, extraction methods, chemical constituents, pharmacological activity and commercial importance of Pterocarpus marsupium so that its potential as a multipurpose medicinal agent can be understood and appreciated.