Journal ArticleDOI
Lead Acetate Toxicity in Rats in Relation to Age and Sex
TLDR
The results indicate a lower toxicity of lead acetate in young animals than in adults and a higher toxicity ofLead in adult males and both groups of young animals.Abstract:
The toxicity of lead acetate was determined in young (3-week-old) and adult (18-week-old) rats of both sexes 8 days after a single i.p. injection. The LD50 was lower in adult males than in adult females and both groups of young animals.read more
Citations
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Journal ArticleDOI
Influence of age on metal metabolism and toxicity.
TL;DR: The results obtained in sucklings show a very high intestinal absorption of all metals which is partly attributed to milk diet; a higher whole body retention, higher blood levels and a much higher accumulation in the brain; and a higher oral toxicity.
Journal ArticleDOI
Blood lead and blood pressure. Relationship in the adolescent and adult US population.
TL;DR: Blood lead levels were significantly higher in younger men and women with high blood pressure, but not in older men or women (aged 56 to 74 years) and dietary calcium and serum zinc levels were inversely related to blood pressure.
Factors influencing metabolism and toxicity of metals: a consensus report
TL;DR: Evidence of interactions among arsenic, cadmium, lead, and mercury, and between these elements and selenium, calcium, copper, zinc, and iron is considered and the possibility of interaction between irritating substances, like tobacco smoke, and the toxicity of metals is discussed.
Journal ArticleDOI
Metabolism of toxic heavy metals in growing organisms: a review.
TL;DR: Current standards on permissive daily exposure to toxic heavy metals should be carefully reconsidered, taking into account the specificities of behavior of heavy metals in growing organism.
Journal ArticleDOI
Acute and chronic effects of neonatal lead exposure on development of the visual evoked response in rats
Donald A. Fox,Donald A. Fox,James P. Lewkowski,James P. Lewkowski,Gary P. Cooper,Gary P. Cooper +5 more
TL;DR: Developmental electrophysiologic studies of the visual evoked response (VER) provided a means for evaluating the effects of lead on central nervous system (CNS) ontogeny and exhibited a significantly decreased CNS recoverability function.
References
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Journal ArticleDOI
Tables for Convenient Calculation of Median-Effective Dose (LD50 or ED50) and Instructions in their Use.
Journal ArticleDOI
Lead Absorption from the Intestine in Newborn Rats
TL;DR: This work has investigated whether one of the reasons for this could be an increased absorption of lead from the intestine during an early stage of life.
Journal ArticleDOI
On the Construction of Tables for Moving-Average Interpolation
TL;DR: In this article, the authors present a simple relation that afford great economies both in construction and in presentation of such tables, and define an f-function and a g-function of the corresponding values of ri as follows:
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Effect of age on gastrointestinal absorption (Fe, Sr, Pb) in the rat.
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