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Lead and protein content of isolated intranuclear inclusion bodies from kidneys of lead-poisoned rats.

Goyer Ra, +3 more
- 01 Mar 1970 - 
- Vol. 22, Iss: 3, pp 245-251
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This article is published in Laboratory Investigation.The article was published on 1970-03-01 and is currently open access. It has received 130 citations till now.

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Journal ArticleDOI

Renal effects of environmental and occupational lead exposure.

TL;DR: Blood lead levels are a poor indicator of body lead burden and reflect recent exposure, and epidemiologic studies have shown an association between blood lead levels and blood pressure, and hypertension is a cardinal feature of lead nephropathy.
Journal ArticleDOI

Experimental enhancement of lead toxicity by low dietary calcium.

TL;DR: It is suggested that at least one dietary factor, low Ca ingestion, influences the pathologic effects of exposure to a specific dose of Pb, and this finding may be particularly relevant to the incidence of toxic manifestations of P b exposure among marginally nourished urban inhabitants.
Journal ArticleDOI

Metal toxicity in the central nervous system.

TL;DR: It has been discovered that microtubules are destroyed by this form of mercury and this effect may explain the inhibition of cell division and cell migration, processes that occur only in the developmental stages, and other hypotheses will stimulate considerable experimental challenges in the future.
Journal ArticleDOI

Lead toxicity: from overt to subclinical to subtle health effects.

TL;DR: Current research implicates lead as a contributing etiologic factor in a number of common diseases affecting large portions of the population such as subtle cognitive and neurological deficits, hypertension, congenital malformations, immunotoxicity, and deficits in growth and development.
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