Journal ArticleDOI
Medicinal Plants Combating Against Insomnia: A Green Anti-Insomnia Approach.
TLDR
This review suggests that medicinal plants are efficacious for insomnia; further laboratory and clinical studies are required.Abstract:
Insomnia is a state defined as trouble with sleep; it is a chronically disabling condition and is now significantly prevalent, imposing enormous health and economic burdens both on individuals and on society. This state includes trouble in falling asleep, problems staying asleep, fragmented sleep (repeatedly awakening at night), and/or awakening before time in the morning. This difficulty in sleeping causes feeling exhausted during the day and trouble with daytime activities including driving, family responsibilities, and completion of valued daily routines. Different types of synthetic sedative drugs are used to handle nervous system changes, but repeated use of sedatives caused tolerance in the human body. After a while, people had to take a heavy dose of sedative to make them feel sleepy, which imposes extra toxic effects on vital organs of the body. Medicinal plants are gaining more and more attention as sedative agents because herbs contained different types of natural bioactive metabolites with not well reported side effects. In addition, medicinal plants have economic, high efficacy and are easy available. So in current review plants possessing sedative activities have been compiled with their constituents responsible to manage insomnia. Review of the literature indicated that medicinal plants from various systems of medicine have been reported to possess sedative activity. This review suggests that medicinal plants are efficacious for insomnia; further laboratory and clinical studies are required.read more
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Effects of Stachys lavandulifolia Vahl on the elevated plus-maze model of anxiety in mice
TL;DR: The results suggested that the extract of Stachys lavandulifolia possessed anxiolytic effect with relatively lower sedative activity than diazepam.
Journal ArticleDOI
Conifers Phytochemicals: A Valuable Forest with Therapeutic Potential.
Kanchan Bhardwaj,Ana Sanches Silva,Maria Atanassova,Rohit Sharma,Eugenie Nepovimova,Kamil Musilek,Ruchi Sharma,Mousa A. Alghuthaymi,Daljeet Singh Dhanjal,Marcello Nicoletti,Bechan Sharma,Navneet Kumar Upadhyay,Natália Cruz-Martins,Prerna Bhardwaj,Kamil Kuca +14 more
TL;DR: An attempt has been made with the intent to highlight the importance of conifer-derived extracts for pharmacological purposes, with the support of relevant in vitro and in vivo experimental data.
Journal ArticleDOI
Ganoderma lucidum promotes sleep through a gut microbiota-dependent and serotonin-involved pathway in mice
Yao Chunyan,Zhiyuan Wang,Huiyong Jiang,Ren Yan,Huang Qianfei,Yin Wang,Hui Xie,Ying Zou,Yu Ying,Longxian Lv +9 more
TL;DR: In this paper, the effect and mechanism of the acidic part of the alcohol extract of Ganoderma lucidum mycelia (GLAA) on sleep were studied in mice and the results showed that GLAA promotes sleep through a gut microbiota-dependent and serotonin-associated pathway in mice.
Journal ArticleDOI
Social Media Big Data-Based Research on the Influencing Factors of Insomnia and Spatiotemporal Evolution
TL;DR: The influencing factors and spatial differentiation of insomnia from the perspective of social media will help relevant professionals better understand the distribution of regional insomnia and provide a reference for related departments to formulate regional insomnia prevention and treatment policies.
References
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Journal ArticleDOI
Epidemiology of insomnia: what we know and what we still need to learn
TL;DR: The association between insomnia and major depressive episodes has been constantly reported: individuals with insomnia are more likely to have a major depressive illness and longitudinal studies have shown that the persistence of insomnia is associated with the appearance of a new depressive episode.
Journal ArticleDOI
Epidemiologic study of sleep disturbances and psychiatric disorders : an opportunity for prevention
TL;DR: As part of the National Institute of Mental Health Epidemiologic Catchment Area study, 7954 respondents were questioned at baseline and 1 year later about sleep complaints and psychiatric symptoms using the Diagnostic Interview Schedule.
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Sleep complaints among elderly persons: an epidemiologic study of three communities.
Daniel J. Foley,Andrew A. Monjan,Brown Sl,Eleanor M. Simonsick,Robert B. Wallace,Dan G. Blazer +5 more
TL;DR: In multivariate analyses, sleep complaints were associated with an increasing number of respiratory symptoms, physical disabilities, nonprescription medications, depressive symptoms and poorer self-perceived health.
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Insomnia: Definition, Prevalence, Etiology, and Consequences
TL;DR: It is estimated that the majority of people with insomnia have an increased risk for comorbid medical disorders, such as conditions causing hypoxemia and dyspnea, gastroesophageal reflux disease, pain conditions, and neurodegenerative diseases.
Journal ArticleDOI
Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy.
TL;DR: Stimulus control and sleep restriction were the most effective single therapy procedures, whereas sleep hygiene education was not effective when used alone.