Journal ArticleDOI
Messung der K + - und Na + -Aktivität mit Mikro-Glaselektroden im Extracellulärraum des Kaninchenskeletmuskels bei Muskelarbeit
G. Gebert,G. Gebert +1 more
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The findings support the assumption that potassium shifts play a role in the regulation of functional hyperemia.Abstract:
Rabbits were anaesthetized with urethane and pentobarbitone sodium. The K+ and Na+ activity in the blood of the femoral vein or in the interstitial space of a skeletal muscle (vastus medialis of M. quadriceps femoris) were measured continuously by means of glass microelectrodes during stimulation of the muscles of the hindlimb. The blood flow in the femoral artery was recorded simultaneously by means of a Statham flowmeter. The K+ activity (at rest about 4 mmole/l) rose during the stimulation of the musculature. The course of the K+ increase was similar to that of the functional hyperemia. Maximum values obtained by frequent supramaximal stimulation (40 cps) were 6–6.5 mmole/l in the venous blood and 8–8.5 mmole/l in the interstitial space. The Na+ activity also rose from about 135 mmole/l to 136–140 mmole/l. The findings support the assumption that potassium shifts play a role in the regulation of functional hyperemia.read more
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Journal ArticleDOI
Dynamics and Consequences of Potassium Shifts in Skeletal Muscle and Heart During Exercise
Ole M. Sejersted,Gisela Sjøgaard +1 more
TL;DR: It is concluded that despite modifying factors coming into play during muscle activity, the K(+) shifts with high-intensity exercise may contribute substantially to fatigue in skeletal muscle, whereas in the heart, except during ischemia, theK(+) balance is controlled much more effectively.
OtherDOI
Circulation to Skeletal Muscle
TL;DR: The sections in this article are: Basal Vascular Resistance and Autoregulation, Role of Myogenic Mechanism in Reactive Hyperemia, and Conclusions.
Journal ArticleDOI
Reflex inputs to the cardiovascular and respiratory centers from dynamically working canine muscles. Some evidence for involvement of group III or IV nerve fibers.
TL;DR: Reflex inputs to the circulatory and ventilator centers from dynamically contracting muscles and their interaction with extramuscular inputs were studied in anesthetized dogs, indicating a relation with similar metabolic processes.
Journal ArticleDOI
Potassium and sodium shifts during in vitro isometric muscle contraction, and the time course of the ion-gradient recovery.
TL;DR: It is concluded that the difference in intracellular potassium concentration in mouse soleus and EDL muscles reflects different activity induced movements of Na and K, and that it is not due to the Na/K pumping ratio.
Journal ArticleDOI
Work-induced potassium changes in skeletal muscle and effluent venous blood assessed by liquid ion-exchanger microelectrodes.
TL;DR: Using liquid ion-exchanger semimicroelectrodes with a side pore, changes of extracellular potassium concentration (Ke+) were measured in adult rabbit and cat gastrocnemius muscles and in venous effluent blood flowing from the cat GastrocNemius muscle during various bouts of activity induced by sciatic nerve stimulation.
References
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Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles.
TL;DR: A method is described for studying transcapillary diffusion of K42 in isolated perfused muscles of dogs and its effects on blood flow and arteriovenous K42 differences are measured.
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The potassium ion as a vasodilator during muscular exercise.
TL;DR: It was calculated that the potassium released during exercise directly explains 25 to 65 per cent of the dilatation during exercise, the percentage being smallest when Dilatation was slightest.
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On the Competition between Metabolic Vasodilatation and Neurogenic Vasoconstriction in Skeletal Muscle1
TL;DR: The resistance vessels and particularly the precapillary sphincters are more sensitive to vasodilator metabolites locally released during exercise than to the vasoconstrictor fibre supply, while the reverse is true for the capacitance vessels.
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