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Metanephric adenoma. A case report and literature review.
Radovan Kaštan,Monika Žižlavská +1 more
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TLDR
The histological differential diagnosis of metanephric adenoma includes papillary renal cell carcinoma in adult patients and nephroblastoma (Wilms tumor), particularly in children, and immunohistochemical examination and cytogenetic analyses may be useful in differential diagnosis.Abstract:
Metanephric adenoma is a rare renal tumor with almost exclusively benign behavior, which can clinically and radiologically imitate malignancy. The histological examination is therefore crucial in diagnosis. We report a case of a 69-year-old female with an incidental finding of metanephric adenoma of the left kidney and synchronous clear cell renal cell carcinoma of the contralateral kidney. In the report, we present our experience with this rare tumor and literature review with focusing on differential diagnosis. The histological differential diagnosis of metanephric adenoma includes papillary renal cell carcinoma in adult patients and nephroblastoma (Wilms tumor), particularly in children. Immunohistochemical examination and cytogenetic analyses may be useful in differential diagnosis of these neoplasms.read more
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Key Renal Neoplasms With a Female Predominance.
TL;DR: This review provides an overview of the clinical, gross, microscopic, immunohistochemical, genetic, and molecular alterations in key renal neoplasms occurring more commonly in females; differential diagnoses are also discussed regardless of sex predilection.
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Atypical metanephric adenoma: Shares similar histopathological features and molecular changes of metanephric adenoma and epithelial-predominant Wilms’ tumor
TL;DR: In this article , the molecular changes in tumors with overlapping morphological features were analyzed, with a median follow-up time of 66 months (range, 8-45 months), even though most patients with WT underwent radiotherapy or chemotherapy after surgery.
References
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Journal ArticleDOI
Prognostic impact of histologic subtyping of adult renal epithelial neoplasms: an experience of 405 cases.
Mahul B. Amin,Mitual Amin,Mitual Amin,Pheroze Tamboli,Javid Javidan,Hans Stricker,Mariza de Peralta Venturina,Anita Deshpande,Mani Menon +8 more
TL;DR: It is shown that the histologic categorization of adult renal epithelial neoplasms performed by routine light microscopic hematoxylin and eosin-based examination in accordance with the contemporary classification scheme has prognostic utility.
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Metanephric adenoma. Clinicopathological study of fifty patients.
TL;DR: 50 examples of an uncommon type of renal adenoma from the files of the Armed Forces Institute of Pathology are reported, appearing to be benign tumors with no malignant potential, and their chief importance is related to the fact that they are most often misinterpreted as renal cell carcinoma or epithelial Wilms' tumor.
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Metastatic metanephric adenoma in a child
TL;DR: It is concluded that tumors with histologic, immunohistochemical, and genetic features characteristic of typical metanephric adenoma can present with metastatic disease.
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Alpha-methylacyl-CoA racemase as a marker in the differential diagnosis of metanephric adenoma
TL;DR: The utility of immunohistochemical staining for Alpha-methylacyl-CoA racemase (AMACR, cytokeratin 7(CK7), CD57 and WT1 to differentiate between the above-mentioned three neoplasms was investigated in this paper.
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Metanephric adenoma of the kidney: clinical and radiological study of nine cases
TL;DR: To analyse the clinical and radiological features of metanephric adenoma (MA, a rare benign renal tumour) in nine patients, and to review previous reports.