Journal ArticleDOI
Nutritional factors in colorectal cancer risk: a case-control study in Majorca
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Investigation in the population of Majorca found that colorectal cancer was found associated with dietary intake of total calories, and a protective effect was associated with the intake of fibre from legumes (pulses) and folic acid.Abstract:
The relationship between energy intake, selected nutrients and colorectal cancer was investigated in the population of Majorca, a Spanish island in the Mediterranean basin. A population-based case-control study using food frequency questionnaires was conducted during the period 1984-1988 and included 286 cases of colorectal cancer, 295 population controls and 203 hospital controls. Food composition tables and ad-hoc estimates of portion sizes were used to derive intake estimates of 29 nutrients and of total calories. Relative risks were calculated for quartiles of consumption of each specific nutrient after adjustment for total calorie intake. Colorectal cancer was found associated with dietary intake of total calories (RRs = 1.0, 1.6, 1.6, 2.6) and cholesterol (RRs = 1.0, 0.9, 1.7, 1.7) and a protective effect was associated with the intake of fibre from legumes (pulses) and folic acid. The associations and the trends were statistically significant. Among the main energy-supplying nutrients, after adjustment for calories from other sources, increased risks were found for protein (RRs = 1.0, 1.1, 1.7, 2.5), notably animal protein, and carbohydrates (RRs = 1.0, 1.5, 1.4, 2.2), whereas no effects were found for increased consumption of lipids or saturated fats.read more
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Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes
Heike A. Bischoff-Ferrari,Edward Giovannucci,Walter C. Willett,Thomas Dietrich,Bess Dawson-Hughes +4 more
TL;DR: Evidence from studies that evaluated thresholds for serum 25(OH)D concentrations in relation to bone mineral density, lower-extremity function, dental health, and risk of falls, fractures, and colorectal cancer suggests that an increase in the currently recommended intake of vitamin D is warranted.
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Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study.
Edward Giovannucci,Meir J. Stampfer,Graham A. Colditz,David J. Hunter,Charles S. Fuchs,Bernard Rosner,Frank E. Speizer,Walter C. Willett +7 more
TL;DR: This report examines the temporal and dosage relations between intake of folate, both from supplements and from foods, and risk for colon cancer in women in the Nurses' Health Study and pays particular attention to the problem of possible confounding by multivitamin use.
Journal Article
Intake of fat, meat, and fiber in relation to risk of colon cancer in men
Edward Giovannucci,Eric B. Rimm,Meir J. Stampfer,Graham A. Colditz,Alberto Ascherio,Walter C. Willett +5 more
TL;DR: The hypothesis that intake of red meat is related to an elevated risk of colon cancer is supported, and a clear association existed between fiber or vegetable intake and risk of Colon cancer.
Journal ArticleDOI
The epidemiology of vitamin D and cancer incidence and mortality: a review (United States).
TL;DR: The biologic evidence for an anti-cancer role of 25(OH)D is also strong for prostate cancer, but the epidemiologic data have not been supportive, and some studies suggest that higher circulating 1,25( OH)2D may be more important than 25(oh)D for protection against aggressive, poorly-differentiated prostate cancer.
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Nutrition and cancer: A review of the evidence for an anti-cancer diet
TL;DR: A diet compiled according to the guidelines here is likely that there would be at least a 60–70 percent decrease in breast, colorectal, and prostate cancers, and even a 40–50 percent reduction in lung cancer, along with similar reductions in cancers at other sites.
References
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Journal ArticleDOI
Total energy intake: implications for epidemiologic analyses
TL;DR: While pitfalls in the manipulation and interpretation of energy intake data in epidemiologic studies have been emphasized, these considerations also highlight the usefulness of obtaining a measurement of total caloric intake, which is not accomplished with nutrient density measures of dietary intake.
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Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices
Bruce K. Armstrong,Richard Doll +1 more
TL;DR: Dietary variables were strongly correlated with several types of cancer, particularly meat consumption with cancer of the colon and fat consumption with cancers of the breast and corpus uteri, suggesting a possible role for dietary factors in modifying the development of cancer at a number of other sites.
Book
The Composition of Foods
TL;DR: Until recently it has generally been the custom in this country to put cases of gonorrhoea on surveillance for three months but that this may not be long enough is suggested in the case described.
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Variations in mortality by weight among 750,000 men and women.
Edward A. Lew,Lawrence Garfinkel +1 more
TL;DR: The mortality findings of this study match closely those of the Build and Blood Pressure Study 1959 based on the experience of 412 million insured persons.
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