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Opioid-Agonists and -Antagonists, Opioid-Receptors

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This article is published in ChemInform.The article was published on 1997-05-27. It has received 65 citations till now. The article focuses on the topics: Opioid.

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Patient-Controlled Analgesia in the Management of Postoperative Pain

TL;DR: With the introduction of an Acute Pain Service, management of postoperative pain can be improved and the use of PCA in hospitals has been increasing because of its proven advantages over conventional intramuscular injections.
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Opioid tolerance: the clinical perspective

TL;DR: Clinical aspects of tolerance and the associated phenomena of dependence, withdrawal and addiction to opioids as they apply to the practice of clinicians who manage patients with chronic malignant and non-malignant pain are discussed.
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Opioidergic and dopaminergic modulation of respiration.

TL;DR: Endogenous dopaminergic modulation in the CNS and carotid bodies enhances CO2-dependent respiratory drive and depresses hypoxic drive, whereas synthetic agonists with selectivity for D1-and D4-types of receptor slow respiratory rhythm, whereas D2-selective agonists modulate acute and chronic responses to hypoxia.
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Rostral ventrolateral medullary opioid receptor subtypes in the inhibitory effect of electroacupuncture on reflex autonomic response in cats

TL;DR: A significant portion of inhibition of the gallbladder pressor response by EA is related to activation of mu- and delta-opioid receptors in the rVLM, which appears to play a role in the EA-related modulation of cardiovascular reflex responses.
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Pathophysiology and Management of Opioid-Induced Pruritus

TL;DR: The current understanding of the mechanisms causing opioid-induced pruritus and the pharmacological therapies available to prevent and/or manage this disorder are summarized.
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