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Book ChapterDOI

Orale Diabetestherapie und ihre experimentellen Grundlagen

Werner Creutzfeldt, +1 more
- pp 1-213
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The article was published on 1960-01-01. It has received 53 citations till now.

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Journal ArticleDOI

An inhibitory effect of tolbutamide and glibenclamide glyburide on the pancreatic islets of normal animals

J. C. Dunbar, +1 more
- 01 Feb 1974 - 
TL;DR: Although insular function tended to return, to normal after treatment was discontinued, the results reported in this paper do not support the generally accepted view that the lasting therapeutic effectiveness of the sulfonylureas is due to a beta-cytotrophic action.
Journal ArticleDOI

Thyroxine treatment and insulin secretion in the rat.

TL;DR: Thyroxine induces a selective inhibition of glucose induced insulin release which is reversed by pyruvate; this indicates that thyroxine interferes with the glycolysis in the beta cell.
Journal ArticleDOI

Reduction in the Activity of the Pancreatic Islets Induced in Normal Rodents by Prolonged Treatment with Derivatives of Sulfonylurea

TL;DR: The islets of animals treated with either drug released less insulin in vitro than those of control animals; the degree of B cell depression was related to the dose of tolbutamide which the animals had received.
Journal ArticleDOI

[Potentiation of the effects of exogenous insulin by N-(4-methylbenzenesulfonyl)-N'-butylurea and N1-n-butylbiguanide in the eviscerated animal].

TL;DR: Ob die Potenzierung der Insulinwirkung durch Biguanide eine wesentliche Bedeutung für deren Wirkungsmechanismus hat, ist fraglich.
References
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Journal ArticleDOI

Influences of glucose loading and of injected insulin on hepatic glucose output.

TL;DR: Special consideration is given to the extent to which these divergencies are due to diflerences in experimental findings brought about by dserences in Experimental conditions and procedures, and are due, on the other hand, to differences in interpretation and calculation.
Journal ArticleDOI

Relationships of pyruvate and lactate during anaerobic metabolism. I. Effects of infusion of pyruvate or glucose and of hyperventilation.

TL;DR: In shock state associated with a reduced or maintained blood flow, an important proportion of muscle lactate release is regulated by a "2 receptor stimulation and not secondary to a reduced oxygen availability", demonstrating that lactate production during shock states is related, at least in part, to increased NaK-ATPase activity under "2 stimulation.
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