Journal ArticleDOI
Patterns of neuroleptic use among the institutionalised elderly.
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TLDR
Marked variation between homes and between wards and hospitals was observed, although for the sample overall associations were observed between disturbed behaviour and mood and the likehood of receiving neuroleptics.Abstract:
A survey was conducted of neuroleptic use amongst the residents of Local Authority homes for the elderly, and elderly patients in geriatric, psychogeriatric and general hospital wards in one of the London boroughs. Some 13% of the residents and patients surveyed were found to have received neuroleptics in the 24 h preceding the survey. Marked variation between homes and between wards and hospitals was observed, although for the sample overall associations were observed between disturbed behaviour and mood and the likelihood of receiving neuroleptics. Issues regarding the use of neuroleptics in the non-psychotic elderly are discussed.read more
Citations
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Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
TL;DR: The prognosis for pregnancies in women with recurrent miscarriage associated with phospholipid antibodies is poor but this randomised controlled trial found that the prognosis improved with low dose aspirin and was further improved with the addition of low dose heparin to the aspirin.
Journal ArticleDOI
Neuroleptic sensitivity in patients with senile dementia of Lewy body type.
TL;DR: Severe, and often fatal, neuroleptic sensitivity may occur in elderly patients with confusion, dementia, or behavioural disturbance and this feature has been included in clinical diagnostic criteria for this type of dementia.
Journal ArticleDOI
Do neuroleptic drugs hasten cognitive decline in dementia? Prospective study with necropsy follow up.
TL;DR: It is suggested that there should be regular review of the need for patients with dementia to continue taking neuroleptic drugs, because they may cause more rapid decline in cognitive function.
Journal ArticleDOI
Pharmacologic Treatment of Agitation Associated With Dementia
Steven C. Risse,Robert A. Barnes +1 more
TL;DR: Because these medications often are given to dementia patients for prolonged periods, studies are needed to define the long‐term clinical efficacy of these agents and environmental, social, or behavioral methods of reducing agitated behaviors need to be explored as an adjunct to any medication trial.
Journal ArticleDOI
A pilot study of haloperidol treatment of psychosis and behavioral disturbance in Alzheimer's disease.
TL;DR: Nine outpatients meeting research criteria for probable Alzheimer's disease who had psychosis or behavioral disturbance participated in a single-blind, placebo-controlled pilot study, finding oral haloperidol in doses of 1 to 5 mg daily improved target symptoms and worsened Modified Mini-Mental State scores.
References
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Journal ArticleDOI
National Patterns of Psychotherapeutic Drug Use
TL;DR: Data on national patterns of use of psychotherapeutic drugs derive from a national sample of American adults, finding that during the year preceding the interview, 13% of the men and 29% ofThe women had used such prescription drugs–in particular minor tranquilizers and daytime sedatives.
Journal ArticleDOI
Prescribing for the elderly.
TL;DR: Today the elderly are the main victims of modern drugs and the system by which they are administered, including dual prescribing systems in hospitals and in general practice, which prevent doctors from being fully responsible for their own prescribing.
Journal ArticleDOI
Use of medicines in general practice.
D C Skegg,R Doll,J Perry +2 more
TL;DR: The prescriptions issued by general practitioners to a population of about 40 000 people were studied and it was found that antimicrobial drugs were prescribed less often than psychotropic drugs, they were given to more people.
Journal ArticleDOI
Efficacy of antipsychotic medications in behaviorally disturbed dementia patients.
TL;DR: It is concluded that antipsychotic medication has a definite but limited therapeutic role in the treatment of behavioral disturbances in nursing home patients with dementia.
Journal ArticleDOI
A survey of prescribing psychotropic drugs in two psychiatric hospitals.
K Michel,T Kolakowska +1 more
TL;DR: Of 511 patients in two psychiatric hospitals, one-fifth had no psychotropic drugs, but over one-third (nearly half of those receiving medication) had a combination of two or more psychotrop drugs.