Pharmacological review on Centella asiatica: A potential herbal cure-all
TLDR
The present review attempts to provide comprehensive information on pharmacology, mechanisms of action, various preclinical and clinical studies, safety precautions and current research prospects of Centella asiatica.Abstract:
In recent times, focus on plant research has increased all over the world. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in the West. Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions. Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition. The present review attempts to provide comprehensive information on pharmacology, mechanisms of action, various preclinical and clinical studies, safety precautions and current research prospects of the herb. At the same time, studies to evaluate the likelihood of interactions with drugs and herbs on simultaneous use, which is imperative for optimal and safe utilization of the herb, are discussed.read more
Citations
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Journal ArticleDOI
Centella asiatica in cosmetology
TL;DR: Research results indicate that Centella asiatica can be used in the treatment of photoaging skin, cellulite and striae.
Journal ArticleDOI
Centella asiatica in Dermatology: An Overview
Wiesława Bylka,Paulina Znajdek-Awiżeń,Elżbieta Studzińska-Sroka,Aleksandra Dańczak-Pazdrowska,Małgorzata Brzezińska +4 more
TL;DR: An overview of current knowledge on the results of scientific in vitro and in vivo experiments focused on the improvement of the healing process of small wounds, hypertrophic scars and burns by C. asiatica is conducted.
Journal ArticleDOI
Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion.
Mehdi Sharifi-Rad,Patrick Valere Tsouh Fokou,Farukh Sharopov,Miquel Martorell,Adedayo O. Ademiluyi,Jovana Rajkovic,Bahare Salehi,Natália Martins,Marcello Iriti,Javad Sharifi-Rad,Javad Sharifi-Rad +10 more
TL;DR: From traditional uses as herbal remedies to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential, comprehensively reviewed the plant sources used as antiulcers agents.
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Wound-healing effect of electrospun gelatin nanofibres containing Centella asiatica extract in a rat model.
TL;DR: It is demonstrated that CA extract facilitates the wound‐repair process by promoting fibroblast proliferation and collagen synthesis and exhibits antibacterial activity and the findings suggest that EGC membranes are a promising material for the treatment of skin wounds.
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Effects of medicinal plants on Alzheimer's disease and memory deficits
Muhammad Akram,Allah Nawaz +1 more
TL;DR: The role of different medicinal plants that play an important role in the treatment of Alzheimer's disease and memory deficits using conventional herbal therapy are reviewed.
References
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Journal ArticleDOI
Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica.
TL;DR: Clinical studies aimed at investigating the sedative, analgesic, antidepressive, antimicrobial, antiviral and immunomodulatory effects that have been demonstrated experimentally are still lacking.
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