Patent
Polybifunctional reagent having a polymeric backbone and latent reactive moieties and bioactive groups
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TLDR
In this paper, a polybifunctional reagent is provided having a polymeric backbone, one or more pendent photoreactive moieties, and two or more bioactive groups.Abstract:
A polybifunctional reagent is provided having a polymeric backbone, one or more pendent photoreactive moieties, and two or more pendent bioactive groups. The reagent can be activated to form a bulk material or can be brought into contact with the surface of a previously formed biomaterial and activated to form a coating. The pendent bioactive groups function by promoting the attachment of specific molecules or cells to the bulk material or coated surface. Bioactive groups can include proteins, peptides, carbohydrates, nucleic acids and other molecules that are capable of binding noncovalently to specific and complimentary portions of molecules or cells.read more
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Patent
Coating for Implantable Devices and a Method of Forming the Same
Syed F. A. Hossainy,Stephen D. Pacetti,Keith E. Fong,Vinayak D. Bhat,Deborra Sanders Millare,Judy A. Guruwaiya,Daryush Mirzaee,Evagenia Mandrusov +7 more
TL;DR: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided in this article, including a method of forming the coatings, which can be used for the delivery of an active ingredient or a combination of active ingredients.
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Apparatus and method for depositing a coating onto a surface of a prosthesis
TL;DR: In this article, a patterned coating on a prosthesis, for example a stent, and a method for forming the coating are disclosed. But they do not specify a procedure for applying the coating to the prosthesis.
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Bioactive agent release coating
TL;DR: A coating composition for use in coating implantable medical devices to improve their ability to release bioactive agents in vivo has been proposed in this article, which includes the bioactive agent in combination with a mixture of a first polymer component such as poly(butyl methacrylate) and a second polymer component (poly(ethylene-co-vinyl acetate).
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Coating composition for multiple hydrophilic applications
TL;DR: In this paper, a coating composition consisting of an aqueous polymeric matrix, a hydrophilic polymer, a colloidal metal oxide and a crosslinker was disclosed.
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Expandable medical device for delivery of beneficial agent
TL;DR: In this paper, a plurality of elongated struts are joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder with a second diameter, and a beneficial agent is loaded into the opening within the strut in layers to achieve desired temporal release kinetics of the agent.
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Journal ArticleDOI
Preparation and Characterization of Au Colloid Monolayers
TL;DR: In this article, the design and initial characterization of two-dimensional arrays of colloidal Au particles are reported, which are prepared by self-assembly of 12 nm diameter colloidal particles onto immobilized polymers having pendant functional groups with high affinity for Au (i.e., CN, SH, and NH 2 ).
Journal ArticleDOI
Silanization of Solid Substrates: A Step Toward Reproducibility
Journal ArticleDOI
Antibiotic peptides as mediators of innate immunity
TL;DR: Antibiotic peptides are amongst the simplest components of the animal's defensive system, which distinguishes environmental microbes from ‘self’, and operate as membrane-active agents, disrupting target-cell permeability.
Patent
Method of improving the biocompatibility of solid surfaces
TL;DR: In this paper, a method for modifying the solid surface to improve its biocompatibility is disclosed, which employs molecules of a bi-compatible agent and a chemical linking moiety possessing a photochemically reactive group.
Patent
Biocompatible coating for solid surfaces
TL;DR: In this paper, a method for modifying the solid surface to improve the biocompatibility of biomaterials having solid surfaces is presented. And the method comprises applying stimulus to sequentially activate the groups and covalently bind the different reactive group of the linking moiety to the molecules of the Biocompatible agent.