Potential biological efficacy of Pinus plant species against oxidative, inflammatory and microbial disorders
Reads0
Chats0
TLDR
The findings of the present study derived the rational for the therapeutic usage of Pinus which is a highly timber yielding plant from Himalayan region, against oxidative, inflammatory and microbial diseases.Abstract:
Traditionally, Pine has been used to treat oxidative and inflammatory disorders. The study was aimed to investigate biological potential of phytoconstituents of Pinus plant species: Pinus roxburghii, Pinus wallichiana and Pinus gerardiana using in-vitro antioxidant, anti-inflammatory and antimicrobial methods. The hydro-alcoholic extraction of dried plant: stem bark was done and the antioxidant activity was evaluated using free radical scavenging methods for 1,1-diphenyl-2-picrylhydrazyl, (DPPH), nitric oxide and hydrogen peroxide radicals, reducing power assays, and total antioxidant capacity. Anti-inflammatory activity was carried out using albumin denaturation and HRBC membrane stabilization assays. Antimicrobial and antifungal activities were also conducted using agar well diffusion method. The qualitative phytochemical analysis of hydro-alcoholic stem bark extracts of three plant species revealed the presence of various biochemical compounds such as alkaloids, flavonoids, glycosides, triterpenoids and saponins. Quantitative phytochemical analysis of plant extracts showed the presence of phenolics, flavonoids, tannins, beta-carotene and lycopene. Plant extracts of three pinus species showed significant antioxidant activity against DPPH, nitric oxide and H2O2 radicals. In in-vitro anti‐inflammatory investigation, Pinus roxburghii exhibited highest protection against albumin denaturation 86.54 ± 1.85 whereas Pinus gerardiana showed 82.03 ± 2.67. Moreover, plant extracts were found to prevent the growth of microorganisms Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Candida albicans showing promising antibacterial and antifungal activities againstCandida albicans. The findings of the present study derived the rational for the therapeutic usage of Pinus which is a highly timber yielding plant from Himalayan region, against oxidative, inflammatory and microbial diseases.read more
Citations
More filters
Journal ArticleDOI
Green and Sustainable Valorization of Bioactive Phenolic Compounds from Pinus By-Products.
TL;DR: The present review is about the reutilization of residues and by-products from the pine species, using ecofriendly technologies to obtain added-value bioactive compounds for industrial applications.
Journal ArticleDOI
In-vitro osteoblast proliferation and in-vivo anti-osteoporotic activity of Bombax ceiba with quantification of Lupeol, gallic acid and β-sitosterol by HPTLC and HPLC.
Shashi Chauhan,Aditi Sharma,Navneet Kumar Upadhyay,Gajender Singh,Uma Ranjan Lal,Rohit Goyal +5 more
TL;DR: Bombax ceiba stem bark ameliorated the state of bone fragility and fracture possibly due to estrogenic modulation, as also confirmed by in-vitro osteogenic activity which may be due to the presence of lupeol, gallic acid and β-sitosterol constituents of the plant.
Journal ArticleDOI
A systematic review of the potential uses of pine bark in food industry and health care
Inés Mármol,Javier Quero,Nerea Jiménez-Moreno,M. Jesús Rodríguez-Yoldi,Carmen Ancín-Azpilicueta +4 more
TL;DR: Both in vitro and in vivo assays suggest a promising future for pine as an adjuvant therapy and the potential of pine bark extract as a source of antioxidant and treatment diseases.
Journal ArticleDOI
Potential anti-inflammatory, antioxidant and antimicrobial activities of Sambucus australis
Jhéssica Benevides Bahiense,Franciane Martins Marques,Mariana Moreira Figueira,Thais Souza Vargas,Tamara P. Kondratyuk,Denise Coutinho Endringer,Rodrigo Scherer,Marcio Fronza +7 more
TL;DR: The results indicate that the ethanol leaf extract of S. australis exhibit prominent anti-inflammatory effects.
Journal ArticleDOI
Chemical Composition of Pinus roxburghii Bark Volatile Oil and Validation of Its Anti-Inflammatory Activity Using Molecular Modelling and Bleomycin-Induced Inflammation in Albino Mice
TL;DR: Pro could serve as a potent anti-inflammatory natural candidate that should be supported by further clinical trials and in silico studies showed that palmitic acid exerted the fittest binding.
References
More filters
Journal ArticleDOI
Studies on products of browning reaction--antioxidative activities of products of browning reaction prepared from glucosamine
TL;DR: The BGA team discusses the development of G-15, which aims to address the challenge of “superbugs” in the high-acid environment.
Journal ArticleDOI
The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals
TL;DR: In this article, it was shown that mulberry leaves contain at least four flavonoids, two of which are rutin and quercetin, and that the scavenging effects of most mulberry extracts were greater than those of rutins (52.0%) at a concentration of 5μg ml −1.
Journal ArticleDOI
Free radicals, antioxidants and functional foods: Impact on human health
TL;DR: The present review provides a brief overview on oxidative stress mediated cellular damages and role of dietary antioxidants as functional foods in the management of human diseases.
Phytochemical screening and Extraction: A Review
TL;DR: An attempt has been made to give an overview of certain extractants and extraction processes with their advantages and disadvantages of bioactive plant constituents.
Journal ArticleDOI
Simple Method for Simultaneous Determination of Chlorophyll and Carotenoids in Tomato Fruit
Masayasu Nagata,Ichiji Yamashita +1 more
TL;DR: In this article, the authors proposed a method to solve the problem of the lack of information in the context of a large number of nodes. But they did not specify how to find the optimal nodes.