Open AccessJournal Article
Practitioners' practical model for managing cancer-related anemia.
TLDR
Data indicate that treatment with darbepoetin alfa, a novel erythropoiesis stimulating protein, improves hemoglobin levels and quality of life in anemic patients with cancer who are not receiving chemotherapy or radiotherapy.Citations
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Anxiety, depression, traumatic stress and quality of life in colorectal cancer after different treatments: A study with Portuguese patients and their partners
TL;DR: Patients who received only surgery, as treatment, had lower levels of depression, anxiety and traumatic stress symptoms when compared with patients who received surgery and chemotherapy or surgery plus radiotherapy.
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Impact of Long‐Acting Growth Factors on Practice Dynamics and Patient Satisfaction
Roy A. Beveridge,Robert M. Rifkin,Ronald J. Moleski,Gary Milkovich,John Reitan,Thomas A. Paivanas,R. Jake Jacobs +6 more
TL;DR: To quantify time expended, patient satisfaction, and econometrics associated with short‐acting and long‐acting growth factors, a large number of studies were conducted on pegfilgrastim and sargramostim.
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The Australian Cancer Anaemia Survey: a snapshot of anaemia in adult patients with cancer.
Tara Seshadri,H. Miles Prince,David R. Bell,Paul Bernard Coughlin,Philip P B James,Gary Richardson,Boris Chern,Peter Briggs,J. E. Norman,Ian N. Olver,Chris Karapetis,John Stewart +11 more
TL;DR: The frequency and management of anaemia in Australian adults with solid and haematological malignancies is evaluated with a focus on children aged between the ages of six and 18 years.
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Cancer-related anemia: clinical review and management update.
Beth Hurter,Nancy Jo Bush +1 more
TL;DR: Oncology nurses play a central role in risk assessment, symptom management, treatment planning, and evaluation and therefore must understand the etiology and physiology of cancer-related anemic states as well as evidence-based interventions to ensure optimal outcomes.
References
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Journal ArticleDOI
Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system
TL;DR: The development and validation of a questionnaire assessing fatigue and anemia-related concerns in people with cancer and its use as a measure of quality of life in cancer treatment and the Fatigue Subscale may also stand alone as a very brief, but reliable and valid measure of fatigue.
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Cloning and expression of the human erythropoietin gene.
Fu-Kuen Lin,Sidney Vaughn Suggs,C H Lin,J K Browne,Richard W. Smalling,Joan C. Egrie,Kenneth Chen,G. M. Fox,F Martin,Z Stabinsky +9 more
TL;DR: The human erythropoietin gene has been isolated from a genomic phage library by using mixed 20-mer and 17-mer oligonucleotide probes and encodes a 27-amino acid signal peptide and a 166-AMino acid mature protein with a calculated Mr of 18,399.
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Isolation and characterization of genomic and cDNA clones of human erythropoietin
Kenneth Jacobs,Charles B. Shoemaker,Richard Rudersdorf,Suzanne D. Neill,Randal J. Kaufman,Allan Mufson,Jasbir Seehra,Simon S. Jones,Rodney M. Hewick,Edward Fritsch,Makoto Kawakita,Tomoe Shimizu,Takaji Miyake +12 more
TL;DR: The cloning of the human erythropoietin gene and the expression of an erythrocytes cDNA clone in a transient mammalian expression system to yield a secreted product with biological activity are described.
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Effects of Epoetin Alfa on Hematologic Parameters and Quality of Life in Cancer Patients Receiving Nonplatinum Chemotherapy: Results of a Randomized, Double-Blind, Placebo-Controlled Trial
TL;DR: Epoetin alfa safely and effectively ameliorates anemia and significantly improves QOL in cancer patients receiving nonplatinum chemotherapy in patients with solid or nonmyeloid hematologic malignancies.
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Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells
TL;DR: DNA cleavage is a major component of normal erythropoiesis, and ERYthropoietin controls erythrocyte production by retarding DNA breakdown and preventing apoptosis in erythroid progenitor cells.