Journal ArticleDOI
Presynaptic effects of morphine and methionine-enkephalin in feline spinal cord.
TLDR
The results of these studies indicate that morphine- and met-enkephalin-induced analgesia is, at least, partly due to the ability of the agents to potentiate “presynaptic inhibition” of nociceptive pathways in the spinal cord.About:
This article is published in Neuropharmacology.The article was published on 1979-04-01. It has received 62 citations till now. The article focuses on the topics: Met-enkephalin & Nociception.read more
Citations
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Journal ArticleDOI
Multiple opiate receptor sites on primary afferent fibres
TL;DR: In this paper, the authors examined the distribution and binding characteristics of opiate receptors on dorsal root and in various regions of the adjacent spinal cord and found that both types of opiates may exist on small-diameter primary afferents.
Journal ArticleDOI
Opiates and opioid peptides hyperpolarize locus coeruleus neurons in vitro.
TL;DR: Opiates and opioid peptides produced a dose-dependent, stereospecific, naloxone-reversible hyperpolarization of the neuronal membrane, associated with an increase in membrane conductance in locus coeruleus neurons.
Book
Control of Nociceptive Transmission in the Spinal Cord
TL;DR: Soldering method comprises placing a cadmium-zinc-lead solder on a copper base and exposing the solder joint to about 200 DEG C. for at least one hour to produce a copper-cadmium -zinc ternary interface barrier layer which inhibits migration.
References
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Journal ArticleDOI
Opiate analgesics inhibit substance P release from rat trigeminal nucleus.
T. M. Jessell,L. L. Iversen +1 more
TL;DR: It is reported here that opiate analgesics are able to suppress the stimulus-evoked release of SP, which may represent a mechanism for the direct spinal analgesic actions of opiates.
Journal ArticleDOI
Analgesia mediated by a direct spinal action of narcotics.
Tony L. Yaksh,T. A. Rudy +1 more
TL;DR: Narcotic analgetics administered directly into the spinal subarachnoid space of the rat via a chronically inserted catheter produce a potent analgesia that can be antagonized by naloxone.
Journal ArticleDOI
Effects of substance P on functionally identified units in cat spinal cord
TL;DR: Results suggest that substance P may be involved in excitatory spinal processes and that its actions may be associated specifically with nociception.
Journal ArticleDOI
Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section.
TL;DR: A localization of receptor binding to the upper dorsal horn is reported and a fall in opiate receptor binding in this area following dorsal root section of rhesus monkey spinal cord is described.
Related Papers (5)
Opiate analgesics inhibit substance P release from rat trigeminal nucleus.
T. M. Jessell,L. L. Iversen +1 more