Journal ArticleDOI
Prostaglandins in umbilical plasma at elective caesarean section
J. G. Bibby,J.D. Brunt,Helena T. Hodgson,Murray D. Mitchell,Anne B. M. Anderson,A. C. Turnbull +5 more
TLDR
Umbilical venous levels of PGE and both arterial and venous Levels of PGF and PGFM were significantly greater after spontaneous labour with vaginal delivery than after elective Caesarean section.About:
This article is published in British Journal of Obstetrics and Gynaecology.The article was published on 1979-04-01. It has received 29 citations till now. The article focuses on the topics: Venous Plasma & Prostaglandin E.read more
Citations
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Journal ArticleDOI
Factors affecting changes in the neonatal systemic circulation.
TL;DR: At birth many major changes must occur in the circulation, and blood flow regulation now assumes greater importance than during fetal life, but little is known about the role of local or humoral factors in controlling the vascular beds of these organs.
Journal ArticleDOI
Prostaglandins during pregnancy and the perinatal period.
TL;DR: Administration of prostaglandins E-2 and F-2{alpha} will provoke contractions of the human uterus at any stage of pregnancy, strongly suggesting that PGE maintains the patency of the ductus arteriosus in utero.
Journal ArticleDOI
The presence or absence of fetal breathing movements predicts the outcome of preterm labour
Bruce M. Castle,A. C. Turnbull +1 more
TL;DR: If the presence of fetal breathing identifies cases in which preterm labour will subside spontaneously, this sign should be of value both in trials of treatment and in clinical management.
BookDOI
Prostaglandins and their inhibitors in clinical obstetrics and gynaecology
TL;DR: The cervix, the uterus, the Fallopian tube, the ovary, and other menstrual disorders are studied.
Journal ArticleDOI
In Vitro Perfusion Studies on Human Umbilical Arteries: I. Vasoactive Effects of Serotonin, PGF2α and PGE2
TL;DR: Serotonin proved to be the most potent vasoconstrictor and the minimum dose required to induce visible pressure responses was 10−9–10−8M of serotonin and 10−7 M of PGF2α and PGE2.
References
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Journal ArticleDOI
Prostaglandins in the circulation of the fetal lamb.
TL;DR: There was a significant decrease in the concentration of PGE and PGF in the plasma of lambs within 12 h after birth compared to the levels found in the same animals as fetuses a few hours previously.
Journal ArticleDOI
Plasma concentrations of prostaglandins during late human pregnancy: influence of normal and preterm labor.
Murray D. Mitchell,A. P. F. Flint,J. G. Bibby,J.D. Brunt,Jill M. Arnold,Anne B. M. Anderson,Alexander C. Aturnbull +6 more
TL;DR: It is concluded that measurement of PGFM concentrations is the most reliable method available of monitoring prostaglandins in the peripheral circulation and that great care must be exercised in the assay and interpretation of prostaglandsin levels in human plasma.
Journal ArticleDOI
Prostaglandin production by intra-uterine tissues from periparturient sheep: use of a superfusion technique.
M. D. Mitchell,A. P. F. Flint +1 more
TL;DR: Oxytocin had no effect on the production of prostaglandins by tissues obtained before labour but myometrium and maternal cotyledon obtained at delivery exhibited a significant increase in production of PGE and PGF (though not PGFM) in response to oxytocin.
Journal ArticleDOI
Metabolism of prostaglandins within the pregnant uterus
TL;DR: Comparison of the levels of enzyme activity in different tissues demonstrates that the greatest metabolism of prostaglandins takes place in the membranes and placenta and that there is much less in the myometrium and the decidua.
Journal ArticleDOI
Effect of prostaglandins E2 and F2α on umbilical blood flow and fetal hemodynamics
Miles J. Novy,Miles J. Novy,George Piasecki,George Piasecki,Benjamin T. Jackson,Benjamin T. Jackson +5 more
TL;DR: The data taken together with the observations of others suggest that prostaglandins may play a role in the circulatory adaptations of the fetus at birth and that PGE2 in high concentrations is likely to have deleterious hemodynamic consequences in the fetus in utero.
Related Papers (5)
The presence or absence of fetal breathing movements predicts the outcome of preterm labour
Bruce M. Castle,A. C. Turnbull +1 more