Showing papers in "The Lancet in 1983"

TL;DR: Gastric biopsy findings are classified according to the type of inflammation, regardless of other features, as "no inflammation", "chronic gastritis", or "active chronic gastritis" (ACG).

TL;DR: A new solid-phase radioimmunoassay for the detection of anticardiolipin antibodies is 200-400 times more sensitive than the precipitation method used in the Venereal Disease Reference Laboratory test and appears to have predictive value for thrombosis in SLE and related disorders.

TL;DR: This mechanism of autoimmune disease induction explains vague associations with viral infections and long latency periods before disease becomes manifest and gives a simple explanation for the well-documented association between HLA-DR and autoimmune diseases in man.

TL;DR: Eleven of 15 sporadic cases of haemolytic uraemic syndrome cases had evidence of infection by VT+ E. coli, suggesting that there was an association between these organisms and these cases of HUS.

TL;DR: The effect of early aggressive antihypertensive treatment on kidney function in diabetic nephropathy was studied prospectively in ten insulin-dependent diabetics and the glomerular filtration rate decreased significantly and the urinary albumin excretion rate and arterial blood pressure rose significantly.

TL;DR: Metronidazole and vancomycin have equivalent efficacy and relapse rates and are tolerated to a similar extent by patients with C-difficile-related diarrhoea and colitis, but metronidrazole is considerably more economical.

TL;DR: Glycopeptides containing polysialic acid units were isolated from human and rat brain and tested for reactivity with antibodies against meningococcal capsules.

TL;DR: With HBIG coverage from birth, the timing of the start of vaccination does not seem to be of importance within the first month of life, but to maximise compliance and minimise costs hepatitis B vaccination should be initiated during the confinement.

TL;DR: Changes in blood pressure in 10 or 15 min periods during which a doctor repeatedly measured blood pressure by the cuff method were monitored by a continuous intra-arterial recorder and there were large differences between individuals in the peak response unrelated to age, sex, baseline blood pressure, or blood-pressure variability.

TL;DR: Patients with stable angina showed frequent, variable, and often asymptomatic electrocardiographic evidence of ischaemia, suggesting that, in such patients, transient impairment in coronary supply may be at least as important as excessive increase in demand in the genesis ofIschaemia during daily life.

TL;DR: High-dose IVGG seems to reduce the frequency of coronary artery abnormalities in patients with Kawasaki disease, and this lesion was confirmed in 1 of the 6 cases in the IVGG group and in 11 of the 19 controls.

TL;DR: Investigation of the expression of class II histocompatibility antigens HLA-DR in the thyrocytes in autoimmune thyroid diseases found it to be one of the earliest manifestations of autoimmune lymphocytic thyroiditis.

TL;DR: Use of the term iodine deficiency disorders, instead of "goitre", would help to bridge the serious gap between knowledge and its application, and the complete eradication of iodine deficiency is therefore feasible within 5-10 years.

TL;DR: A British prisoner serving a life term for sexual offenses who alleged that he was forcibly subjected to treatment with psychoactive drugs is described, and the judge ruled that the prisoner had failed to prove absence of consent.

TL;DR: Gated, pulsed, doppler ultrasound was used to study blood flow velocity profiles in the uterine vessels during the second and third trimesters of pregnancy to give early warning of impaired uteroplacental perfusion and can be used to evaluate methods of improving uterine blood flow.

TL;DR: The association between low selenium level and cancer was strongest for gastrointestinal and prostatic cancers and Serum levels of vitamins A and E compounded the effect of low Selenium.

TL;DR: There was an excess of deaths from cardiac and external causes on the days after the major earthquake in Athens in 1981, but no excess of died from cancer and little, if any, excess of death from other causes.

TL;DR: The combined findings of both studies support the decreased use of serotonin in suicide victims and may also throw light on the mechanism of action of antidepressant drugs.

TL;DR: It is suggested here that in most cases of Parkinson's disease the cause may be an environmental factor, possibly toxic, superimposed on a background of slow, sustained neuronal loss due to advancing age.

TL;DR: 1 previously untreated patient with plasma-cell leukaemia and 8 patients with myeloma were treated with high-dose melphalan 100-140 mg/m2 iv and 3 of the 5 previously untreated patients achieved biochemical and bone-marrow complete remissions.

TL;DR: In accordance with a previous protocol, a second cohort of 254 mothers with a history of previous neural tube defect births was before a subsequent conception and continued until the time of the second missed menstrual period, finding no recurrences among the offspring of a further 114 mothers whose duration of supplementation fell short of the full regimen.

TL;DR: Brahms argues that a physician's responsibility to these young patients is greater than that to older girls and that the final decision on whether or not to notify parents should rest with the doctor rather than the patient.

TL;DR: The results suggest that mild xerophthalmia justifies vigorous community-wide intervention, as much to reduce childhood mortality as to prevent blindness, and that night blindness and Bitot's spots are as important as anthropometric indices in screening children to determine which of them need medical and nutritional attention.