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Open AccessJournal ArticleDOI

Quinoline N-oxides and hydroxamic acids with antibacterial properties

R. T. Coutts, +2 more
- 01 Aug 1970 - 
- Vol. 48, Iss: 15, pp 2393-2396
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TLDR
A number of quinoline Noxides have been prepared and oxidized by means of lead tetraacetate to Quinoline hydroxamic acids (i.e. derivatives of 1-hydroxy-2(1H)-quinolone) as mentioned in this paper.
Abstract
A number of quinoline N-oxides have been prepared and oxidized by means of lead tetraacetate to quinoline hydroxamic acids (i.e. derivatives of 1-hydroxy-2(1H)-quinolone). Contrary to the findings ...

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Structure-based design of inhibitors of the rice blast fungal enzyme trihydroxynaphthalene reductase.

TL;DR: This work used the LeapFrog program to develop a docking model for interaction of ligands with the active site of THNR and synthesized inhibitors in the nanomolar range and developed several inhibitors that did not conform to the properties of the THNR active site.
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Enzymatic synthesis of fatty hydroxamic acid derivatives based on palm kernel oil.

TL;DR: Fatty hydroxamic acid derivatives were synthesized using Lipozyme TL IM catalyst at biphasic medium as the palm kernel oil was dissolved in hexane and hydroxylamine derivatives were dissolved in water to achieve the highest conversion percentage of product.
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An improved method for the synthesis of 3-amino-1h-quinolin-2-one

TL;DR: In this article, an efficient method for the synthesis of 3-amino-1H-quinolin-2-one was described, which upon isomerization with light, cyclization and hydrolysis afforded the desired product.
Journal ArticleDOI

Half-Wave Potentials of 1-AZA- and 1,8-Diazaanthraquinones

TL;DR: In this paper, the redox properties of a series of 1-azaanthracene-9,10-diones, 1-8-diazaanthracenes, 2-pyridone moiety is a stronger electron acceptor than pyridine ring, in agreement with reactivity data.