Journal ArticleDOI
Sarcoidosis of the Peripheral Nerve: Clinical, Electrophysiological and Histological Study of Two Cases
Giuliana Galassi,Milena Gibertoni,A. M. Mancini,Raffaello Nemni,Giorgia Volpi,Elisa Merelli,Giorgio Vacca +6 more
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TLDR
Two cases of sarcoid polyneuropathy were diagnosed by histological examination of the nerve biopsy, and the electrophysiological findings in both patients suggested a neuropathy of axonal type, confirmed by a morphological study of a sural nerveBiopsy.Abstract:
Two cases of sarcoid polyneuropathy were diagnosed by histological examination of the nerve biopsy. The electrophysiological findings in both patients suggested a neuropathy of axonal type, confirmed by a morphological study of a sural nerve biopsy by light microscopy and on teased-fiber preparations. The sarcoid granulomas were multiple, especially in case 2; they were sparse in the epineurial and perineurial spaces and absent in the endoneurium, whose interstitial component contained cellular infiltrations of scattered macrophages. Blood vessel changes were a constant morphological feature. The mechanisms that possibly contribute to the pathogenesis of the sarcoid neuropathy are discussed in relation to previous reports.read more
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AAEE minimonograph #26: The electrodiagnosis of carpal tunnel syndrome
TL;DR: The electrodiagnosis of carpal tunnel syndrome is reviewed, including discussions of old and new techniques of motor and sensory nerve conduction, anomalous innervation, and needle electrode examination.
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Neurosarcoidosis: a clinical dilemma.
TL;DR: The clinical manifestations of neurosarcoidosis, diagnostic dilemmas and considerations, and therapy are described, and the value of new drugs such as anti-tumour necrosis factor alpha will be assessed.
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The Clinical Features of Sarcoidosis: A Comprehensive Review.
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Nerve granulomas and vasculitis in sarcoid peripheral neuropathy: a clinicopathological study of 11 patients.
Gérard Said,Catherine Lacroix,Violaine Planté-Bordeneuve,Laurence Le Page,Fernando Pico,Olivier Presles,Jacques Senant,Pascal Remy,Philippe Rondepierre,Jacques Mallecourt +9 more
TL;DR: The wide range of clinical manifestations of sarcoid neuropathy and the frequent association of granulomatous inflammatory infiltrates with necrotizing vasculitis and with silent or symptomatic involvement of other organs are illustrated.
Journal ArticleDOI
AAEM minimonograph #34: Polyneuropathy: Classification by nerve conduction studies and electromyography
TL;DR: The electrodiagnostic classification of polyneuropathy is associated with morphologic correlates and is based upon determining involvement of sensory and motor fibers and distinguishing between predominantly axon loss and demyelinating lesions.