Journal ArticleDOI
Secondary Sexual Characteristics and Menses in Young Girls Seen in Office Practice: A Study from the Pediatric Research in Office Settings Network
Marcia E. Herman-Giddens,Eric J. Slora,Richard C. Wasserman,Richard C. Wasserman,Carlos J. Bourdony,Manju V. Bhapkar,Gary G. Koch,Cynthia M. Hasemeier +7 more
Reads0
Chats0
TLDR
Data suggest that girls seen in a sample of pediatric practices from across the United States are developing pubertal characteristics at younger ages than currently used norms, and practitioners may need to revise their criteria for referral of girls with precocious puberty.Abstract:
Objective. To determine the current prevalence and mean ages of onset of pubertal characteristics in young girls seen in pediatric practices in the United States. Methods. A cross-sectional study was conducted by 225 clinicians in pediatric practices belonging to Pediatric Research in Office Settings, a practice-based research network. After standardized training in the assessment of pubertal maturation, practitioners rated the level of sexual maturation on girls 3 through 12 years who were undergoing complete physical examinations. Results. Data were analyzed for 17 077 girls, of whom 9.6% were African-American and 90.4% white. At age 3, 3% of African-American girls and 1% of white girls showed breast and/or pubic hair development, with proportions increasing to 27.2% and 6.7%, respectively, at 7 years of age. At age 8, 48.3% of African-American girls and 14.7% of white girls had begun development. At every age for each characteristic, African-American girls were more advanced than white girls. The mean ages of onset of breast development for African-American and white girls were 8.87 years (SD, 1.93) and 9.96 years (SD, 1.82), respectively; and for pubic hair development, 8.78 years (SD, 2.00) and 10.51 years (SD, 1.67), respectively. Menses occurred at 12.16 years (SD, 1.21) in African-American girls and 12.88 years (SD, 1.20) of age in white girls. Conclusions. These data suggest that girls seen in a sample of pediatric practices from across the United States are developing pubertal characteristics at younger ages than currently used norms. Practitioners may need to revise their criteria for referral of girls with precocious puberty, with attention to racial differences.read more
Citations
More filters
Journal ArticleDOI
mice: Multivariate Imputation by Chained Equations in R
TL;DR: Mice adds new functionality for imputing multilevel data, automatic predictor selection, data handling, post-processing imputed values, specialized pooling routines, model selection tools, and diagnostic graphs.
Book
Exacting Beauty: Theory, Assessment, and Treatment of Body Image Disturbance
TL;DR: The Scope of Body Image Disturbance - the Big Picture An Overview of Assessment and Treatment Strategies Sociocultural Theory - the Media and Society Social Comparison Processes Appearance-Related Feedback Interpersonal Factors Peers, Parents and Perfect Strangers Feminist Perspectives Sexual Abuse and Sexual Harassment Behavioural Aspects of Disturbances - Conditioning, Context and Avoidance Cognitive Processing Models Future Directions - Integrative Theories, Multidimensional Assessment and Multicomponent Interventions
Journal ArticleDOI
The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration
Anne-Simone Parent,Grete Teilmann,Anders Juul,Niels E. Skakkebæk,Jorma Toppari,Jean-Pierre Bourguignon +5 more
TL;DR: These observations urge further study of the onset of puberty as a possible sensitive and early marker of the interactions between environmental conditions and genetic susceptibility that can influence physiological and pathological processes.
Journal ArticleDOI
State of the Science of Endocrine Disrupting Chemicals - 2012
TL;DR: The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of UNEP or WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.
The Practice Committee of the American Society for Reproductive Medicine
TL;DR: This document reviews the scientific background, current technology, clinical results and potential future applications of two methods for preserving female fertility—ovarian tissue cryopreservation and oocyte cryopReservation.
References
More filters
Journal ArticleDOI
Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease
Nathan Mantel,William Haenszel +1 more
TL;DR: In this paper, the role and limitations of retrospective investigations of factors possibly associated with the occurrence of a disease are discussed and their relationship to forward-type studies emphasized, and examples of situations in which misleading associations could arise through the use of inappropriate control groups are presented.
Journal ArticleDOI
Variations in pattern of pubertal changes in girls.
W. A. Marshall,James M. Tanner +1 more
TL;DR: The extent of normal individual variation observed in the events of puberty among the girls of the Harpenden Growth Study is described.
Book
Nelson textbook of pediatrics
TL;DR: It is Nelson that the authors' own lawyers consider to be the ‘Bible’ on paediatric matters, and to have reached a 15th edition is an achievement in itself, having taken 63 years in the process.
Journal ArticleDOI
Variations in the Pattern of Pubertal Changes in Boys
W. A. Marshall,James M. Tanner +1 more
TL;DR: Mixed longitudinal data on the physical changes at puberty in 228 normal boys are presented together with normal standards for stages of genital and pubic hair development, finding that boys' genitalia begin to develop only about 6 months later than the girls' breasts and Pubic hair appears about 1½ years later in boys than in girls.