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Sensitivity via the complex-step method for delay differential equations with non-smooth initial data

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TLDR
In this paper, the authors used the complex-step derivative approximation technique to compute sensitivities for delay differential equations (DDEs) with non-smooth (discontinuous and even distributional) history functions.
Abstract
In this report, we use the complex-step derivative approximation technique to compute sensitivities for delay differential equations (DDEs) with non-smooth (discontinuous and even distributional) history functions. We compare the results with exact derivatives and with those computed using the classical sensitivity equations whenever possible. Our results demonstrate that the implementation of the complex-step method using the method of steps and the Matlab solver dde23 provides a very good approximation of sensitivities as long as discontinuities in the initial data do not cause loss of smoothness in the solution: that is, even when the underlying smoothness with respect to the initial data for the Cauchy-Riemann derivation of the the method does not hold. We conclude with remarks on our findings regarding the complex-step method for computing sensitivities for simpler ordinary differential equation systems in the event of lack of smoothness with respect to parameters.

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Journal ArticleDOI

Modeling Zika Virus Transmission Dynamics: Parameter Estimates, Disease Characteristics, and Prevention.

TL;DR: A method that utilizes a mathematical model of ZIKV dynamics and the complex-step derivative approximation technique to identify parameters that can be estimated from the available data and found that peak prevalence can be reduced to nearly 10% by reducing mosquito-to-human contact or increasing mosquito death by at least a factor of three of the base case.

Sensitivity analysis in poro-elastic and poro-visco-elastic models

TL;DR: In this article, a sensitivity analysis on the solutions of these fluid-solid mixtures problems with respect to the imposed boundary data is performed, which is the first step towards optimization and control problems associated with these models.
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Poro-visco-elastic models in biomechanics: sensitivity analysis

TL;DR: Sensitivity analysis provides valuable insights about how robust the system is with respect to changes in parameters and data and reveals which ones are the most influential for the solutions, and could potentially be used as control agents.
References
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Book

Delay Differential Equations: With Applications in Population Dynamics

Yang Kuang
TL;DR: Delay Differential Equations as mentioned in this paper are a generalization of delay differential equations and have been used in a variety of applications in population dynamics, such as global stability for single species models and multi-species models.
Journal ArticleDOI

The complex-step derivative approximation

TL;DR: Improvements to the basic method are suggested that further increase its accuracy and robustness and unveil the connection to algorithmic differentiation theory.
Book

Integrodifferential Equations and Delay Models in Population Dynamics

TL;DR: In this paper, the authors proposed a delay logistic with a constant time lag for a single species and showed that the delay can stabilize an otherwise unstable equilibrium in a predator-parrot system.
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